Hoxd and Gli3 interactions modulate digit number in the amniote limb (Q28508727)

Homeobox D13

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GLI-Kruppel family member GLI3

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Homeobox D12

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Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning

author name string

Rushikesh Sheth

series ordinal

1

1 reference

24 January 2017

M. Félix Bastida

series ordinal

2

1 reference

24 January 2017

Marian Ros

series ordinal

3

1 reference

24 January 2017

language of work or name

English

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publication date

15 October 2007

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24 January 2017

Developmental Biology

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24 January 2017

310

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24 January 2017

2

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24 January 2017

430–441

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24 January 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Levels of Gli3 repressor correlate with Bmp4 expression and apoptosis during limb development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

An I47L substitution in the HOXD13 homeodomain causes a novel human limb malformation by producing a selective loss of function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Ectopic expression of Hoxb-8 causes duplication of the ZPA in the forelimb and homeotic transformation of axial structures.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Direct interaction with Hoxd proteins reverses Gli3-repressor function to promote digit formation downstream of Shh.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Developmental basis of limblessness and axial patterning in snakes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Patterning in the vertebrate limb

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Colinearity and functional hierarchy among genes of the homeotic complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Birth and death of cells in limb development: a mapping study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Ihh controls cartilage development by antagonizing Gli3, but requires additional effectors to regulate osteoblast and vascular development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Serial deletions and duplications suggest a mechanism for the collinearity of Hoxd genes in limbs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

An estimate of the population frequency of congenital malformations of the upper limb

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

A gene complex controlling segmentation in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

The roles of FGFs in the early development of vertebrate limbs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

A duplicated zone of polarizing activity in polydactylous mouse mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Multigenic control of the localization of the zone of polarizing activity in limb morphogenesis in the mouse.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

High-resolution mapping of the Gli3 mutation extra-toes reveals a 51.5-kb deletion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

In situ hybridization analysis of chick embryos in whole mount and tissue sections.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Differential regulation of gene expression in the digit forming area of the mouse limb bud by SHH and gremlin 1/FGF-mediated epithelial-mesenchymal signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Sonic hedgehog mediates the polarizing activity of the ZPA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

A syndactyly type IV locus maps to 7q36.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Hox gene expression in teleost fins and the origin of vertebrate digits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

A global control region defines a chromosomal regulatory landscape containing the HoxD cluster

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Transition of Hox expression during limb cartilage development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Hox transcription factors and their elusive mammalian gene targets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Control of Hoxd genes' collinearity during early limb development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Regulatory constraints in the evolution of the tetrapod limb anterior-posterior polarity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Positional signalling and specification of digits in chick limb morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Gene transpositions in the HoxD complex reveal a hierarchy of regulatory controls.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

A group 13 homeodomain is neither necessary nor sufficient for posterior prevalence in the mouse limb.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Misexpression of Hoxa-13 induces cartilage homeotic transformation and changes cell adhesiveness in chick limb buds.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Evidence for regulation of cartilage differentiation by the homeobox gene Hoxc-8.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Synpolydactyly in mice with a targeted deficiency in the HoxD complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Hox genes in digit development and evolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Regulation of number and size of digits by posterior Hox genes: A dose-dependent mechanism with potential evolutionary implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

A dual role for Hox genes in limb anterior-posterior asymmetry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Interactions between HOXD and Gli3 genes control the limb apical ectodermal ridge via Fgf10.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023

Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.07.023