Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity (Q28505683)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

Ribonuclease H2, subunit B

8 February 2020

main subject

1 reference

GOA release 2020-03-11

author

Martin Achleitner

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Rayk Behrendt

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

Bjoern Hiller

1

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Silke Glage

3

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Ronald Naumann

4

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Axel Roers

6

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

language of work or name

English

0 references

publication date

16 July 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

8 February 2020

published in

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

209

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

8

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

1419-1426

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

PCNA directs type 2 RNase H activity on DNA replication and repair substrates

8 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Trex1 prevents cell-intrinsic initiation of autoimmunity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Functional role of type I and type II interferons in antiviral defense

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Genome instability due to ribonucleotide incorporation into DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Transmission distortion by loss of p21 or p27 cyclin-dependent kinase inhibitors following competitive spermatogonial transplantation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Ribonuclease H: the enzymes in eukaryotes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

B lymphocyte-specific, Cre-mediated mutagenesis in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Enzymatic completion of mammalian lagging-strand DNA replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Site-specific ribonuclease activity of eukaryotic DNA topoisomerase I.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409502

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

2 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20120876

Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20120876

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20120876

A reliable lacZ expression reporter cassette for multipurpose, knockout-first alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20120876

Type I interferonopathies: a novel set of inborn errors of immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20120876

21 January 2018

Identifiers

DOI

10.1084/JEM.20120876

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

release_ppcznodmb5bzlb5zrru5d4b6bq

8 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ppcznodmb5bzlb5zrru5d4b6bq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22802351%20AND%20SRC:MED&resulttype=core&format=json