Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice (Q28487437)

7

object named as

Panayiotis P Constantinides

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author name string

Gerardo G Mackenzie

1

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Liqun Huang

2

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Ninche Alston

3

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Nengtai Ouyang

4

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Kvetoslava Vrankova

5

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George Mattheolabakis

6

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Basil Rigas

Creative Commons Attribution 4.0 International

8

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language of work or name

English

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publication date

2013

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published in

PLOS One

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volume

8

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issue

5

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page(s)

e61532

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copyright license

start time

1 May 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Mitochondrial-targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen species

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Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces or

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The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2

29 September 2017

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Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3.

29 September 2017

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Activated signal transducer and activator of transcription 3 (STAT3) supports the malignant phenotype of human pancreatic cancer.

29 September 2017

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061532

Tumour growth inhibition of human pancreatic cancer xenografts in SCID mice by cimetidine

21 January 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061532

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23650499

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0061532

1 reference

2171070

ADS bibcode

2013PLoSO...861532M

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2171070

1 reference

1 reference

1 reference