Combinatorial pharmacogenetic interactions of bucindolol and β1, α2C adrenergic receptor polymorphisms (Q28484344)

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object named as

Christopher M O'Connor

Christopher M

O'Connor

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20 October 2023

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William T Abraham

William T

Abraham

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Mona Fiuzat

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Mona

Fiuzat

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Peter E Carson

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Peter E

Carson

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Jonathan F Plehn

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Jonathan F

Plehn

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Stephen S Gottlieb

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Stephen S

Gottlieb

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Marc A Silver

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Marc A

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JoAnn Lindenfeld

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JoAnn

Lindenfeld

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Alan B Miller

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Alan B

Miller

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Michel White

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Michel

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Ryan Walsh

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Ryan

Walsh

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Penny Nelson

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Penny

Nelson

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Allen Medway

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Allen

Medway

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Gordon Davis

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Gordon

Davis

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Alastair D Robertson

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Alastair D

Robertson

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J David Port

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J David

Port

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James Carr

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James

Carr

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Guinevere A Murphy

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Guinevere A

Murphy

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Stephen B Liggett

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Stephen B

Liggett

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Michael R Bristow

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Michael R

Creative Commons CC0 License

Bristow

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20 October 2023

language of work or name

English

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publication date

2012

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published in

PLOS One

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volume

7

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issue

10

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page(s)

e44324

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copyright license

start time

10 October 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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cites work

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A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure

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Greater inotropic and cyclic AMP responses evoked by noradrenaline through Arg389 beta 1-adrenoceptors versus Gly389 beta 1-adrenoceptors in isolated human atrial myocardium

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Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure

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A four amino acid deletion polymorphism in the third intracellular loop of the human alpha 2C-adrenergic receptor confers impaired coupling to multiple effectors

29 September 2017

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Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission

29 September 2017

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Mechanism of Action of Bucindolol in Human Ventricular Myocardium

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An alpha2C-adrenergic receptor polymorphism alters the norepinephrine-lowering effects and therapeutic response of the beta-blocker bucindolol in chronic heart failure

27 November 2018

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Lack of association between adrenergic receptor genotypes and survival in heart failure patients treated with carvedilol or metoprolol

27 November 2018

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Effect of baseline or changes in adrenergic activity on clinical outcomes in the beta-blocker evaluation of survival trial.

27 November 2018

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β1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure

27 November 2018

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An evaluation of the beta-1 adrenergic receptor Arg389Gly polymorphism in individuals with heart failure: a MERIT-HF sub-study

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based on heuristic

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