PRC2/EED-EZH2 complex is up-regulated in breast cancer lymph node metastasis compared to primary tumor and correlates with tumor proliferation in situ (Q28484272)

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English	PRC2/EED-EZH2 complex is up-regulated in breast cancer lymph node metastasis compared to primary tumor and correlates with tumor proliferation in situ	scientific article

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20 February 2020

PRC2/EED-EZH2 complex is up-regulated in breast cancer lymph node metastasis compared to primary tumor and correlates with tumor proliferation in situ (English)

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20 February 2020

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Susan P. Holmes

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20 February 2020

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Hongxiang Yu

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20 February 2020

Diana L Simons

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Ilana Segall

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20 February 2020

Valeria Carcamo-Cavazos

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20 February 2020

Erich J Schwartz

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20 February 2020

Ning Yan

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20 February 2020

Neta S Zuckerman

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20 February 2020

Frederick M Dirbas

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20 February 2020

Denise L Johnson

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20 February 2020

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10 December 2012

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20 February 2020

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20 February 2020

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20 February 2020

e51239

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20 February 2020

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20 February 2020

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Creative Commons Attribution 4.0 International

10 December 2012

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Quantitative, architectural analysis of immune cell subsets in tumor-draining lymph nodes from breast cancer patients and healthy lymph nodes

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MYC stimulates EZH2 expression by repression of its negative regulator miR-26a

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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

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The polycomb group protein EZH2 is involved in progression of prostate cancer

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Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

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Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer

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29 September 2017

Myc regulates the transcription of the PRC2 gene to control the expression of developmental genes in embryonic stem cells

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Myc enforces overexpression of EZH2 in early prostatic neoplasia via transcriptional and post-transcriptional mechanisms

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Cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation of enhancer of zeste 2 (Ezh2) regulates its stability

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MEK-ERK pathway regulates EZH2 overexpression in association with aggressive breast cancer subtypes

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EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

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Molecular Portraits and 70-Gene Prognosis Signature Are Preserved throughout the Metastatic Process of Breast Cancer

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A gene expression signature that defines breast cancer metastases

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Differentially expressed genes between primary cancer and paired lymph node metastases predict clinical outcome of node-positive breast cancer patients

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10.1371/JOURNAL.PONE.0051239

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20 February 2020

2012PLoSO...751239Y

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20 February 2020

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20 February 2020

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