On the mechanism of action of SJ-172550 in inhibiting the interaction of MDM4 and p53 (Q28484086)

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3 February 2020

title

On the mechanism of action of SJ-172550 in inhibiting the interaction of MDM4 and p53 (English)

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1

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Michal Bista

2

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Benedykt Wladyka

12

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Grzegorz Dubin

15

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R. Kiplin Guy

16

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13

Sylwia Kedracka-Krok

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author name string

David Smithson

3

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Aleksandra Pecak

4

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Gabriella Salinas

5

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Katarzyna Pustelny

6

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Jaeki Min

7

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Artur Pirog

8

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Kristin Finch

9

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Michal Zdzalik

10

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Brett Waddell

11

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Michael A Dyer

14

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language of work or name

English

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publication date

4 June 2012

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volume

7

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issue

6

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3 February 2020

page(s)

e37518

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Creative Commons Attribution 4.0 International

3 February 2020

copyright license

start time

4 June 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX

19 March 2017

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The genetics of the p53 pathway, apoptosis and cancer therapy

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Methylsulfonylnitrobenzoates, a new class of irreversible inhibitors of the interaction of the thyroid hormone receptor and its obligate coactivators that functionally antagonizes thyroid hormone.

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An illegitimate microRNA target site within the 3' UTR of MDM4 affects ovarian cancer progression and chemosensitivity

29 September 2017

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A stapled p53 helix overcomes HDMX-mediated suppression of p53.

29 September 2017

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Identification and characterization of the first small molecule inhibitor of MDMX

29 September 2017

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Neratinib: an oral, irreversible dual EGFR/HER2 inhibitor for breast and non-small cell lung cancer

29 September 2017

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Irreversible pan-ErbB tyrosine kinase inhibitors and breast cancer: current status and future directions.

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MDM4 (MDMX) and its Transcript Variants.

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P2Y(12) inhibitors: differences in properties and mechanisms of action and potential consequences for clinical use.

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Improvement of pharmacological properties of irreversible thyroid receptor coactivator binding inhibitors.

29 September 2017

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MDMX: from bench to bedside

29 September 2017

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Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery.

2 June 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037518

10.1371/JOURNAL.PONE.0037518

21 January 2018

Identifiers

DOI

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3 February 2020

ADS bibcode

2012PLoSO...737518B

0 references

1 reference

2 references

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3 February 2020

2 references

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