TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model (Q28478908)

Ido Goldstein

5

0 references

Ran Brosh

Ran Brosh

6

0 references

Varda Rotter

14

Varda Rotter

0 references

Shalom Madar

2

Shalom Madar

0 references

Ira Kogan-Sakin

3

Ira Kogan-Sakin

0 references

Iris Kamer

4

Iris Kamer

0 references

Naomi Goldfinger

11

Naomi Goldfinger

0 references

author name string

Orit Leshem

1

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Yehudit Cohen

7

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Marcelo Ehrlich

9

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Shmuel Ben-Sasson

10

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Ron Loewenthal

12

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Ephraim Gazit

13

0 references

Raanan Berger

Creative Commons Attribution 4.0 International

15

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language of work or name

English

0 references

publication date

2011

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published in

PLOS One

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volume

6

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issue

7

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page(s)

e21650

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copyright license

start time

1 July 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

PrEC LHSR

0 references

cites work

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19 March 2017

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TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions

19 March 2017

1 reference

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Three-color FISH analysis of TMPRSS2/ERG fusions in prostate cancer indicates that genomic microdeletion of chromosome 21 is associated with rearrangement

19 March 2017

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19 March 2017

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Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail

19 March 2017

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FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-to-mesenchymal transition in human prostate cancer cells.

19 March 2017

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29 September 2017

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ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells

29 September 2017

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Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer

29 September 2017

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miR-200 regulates PDGF-D-mediated epithelial-mesenchymal transition, adhesion, and invasion of prostate cancer cells

29 September 2017

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29 September 2017

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Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

29 September 2017

1 reference

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ZEB1 enhances transendothelial migration and represses the epithelial phenotype of prostate cancer cells

29 September 2017

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Hepatocyte growth factor activator inhibitor type 1 regulates epithelial to mesenchymal transition through membrane-bound serine proteinases

29 September 2017

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29 September 2017

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Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts

29 September 2017

1 reference

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Epithelial to mesenchymal transition of a primary prostate cell line with switches of cell adhesion modules but without malignant transformation

29 September 2017

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Modulated expression of WFDC1 during carcinogenesis and cellular senescence

29 September 2017

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Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer

29 September 2017

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29 September 2017

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TMPRSS2:ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis.

29 September 2017

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Insulin-like growth factor-I-dependent up-regulation of ZEB1 drives epithelial-to-mesenchymal transition in human prostate cancer cells

29 September 2017

1 reference

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A causal role for ERG in neoplastic transformation of prostate epithelium.

29 September 2017

1 reference

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Proteomics analysis of Hodgkin lymphoma: identification of new players involved in the cross-talk between HRS cells and infiltrating lymphocytes

29 September 2017

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Suppression of hepatocyte growth factor activator inhibitor-1 leads to a more aggressive phenotype of prostate cancer cells in vitro

29 September 2017

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Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer

29 September 2017

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Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model.

29 September 2017

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TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming

29 September 2017

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The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

29 September 2017

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ETS rearrangements and prostate cancer initiation

2 June 2018

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TMPRSS2-ERG fusion is frequently observed in Gleason pattern 3 prostate cancer in a Canadian cohort

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128608

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2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128608

Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128608

Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128608

Establishing the robustness of short-tandem-repeat statistics for forensic applications

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128608

TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer.

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021650

TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021650

TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021650

A novel biomarker for staging human prostate adenocarcinoma: overexpression of matriptase with concomitant loss of its inhibitor, hepatocyte growth factor activator inhibitor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021650

TMPRSS2-ERG Fusion Prostate Cancer: An Early Molecular Event Associated With Invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021650

Chromosome Mechanisms Giving Rise to the TMPRSS2-ERG Fusion Oncogene in Prostate Cancer and HGPIN Lesions

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21747944

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0021650

1 reference

4731445

ADS bibcode

2011PLoSO...621650L

0 references

4731445

1 reference

1 reference

1 reference