Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth (Q28473419)

2

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Masahiro Hiasa

3

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Asuka Oda

4

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Hiroe Amou

5

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Shinsuke Kido

6

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Takeshi Harada

7

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Osamu Tanaka

8

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Hirokazu Miki

9

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Shingen Nakamura

10

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Ayako Nakano

11

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Kumiko Kagawa

12

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Kenichiro Yata

13

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Shuji Ozaki

14

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Toshio Matsumoto

Creative Commons Attribution 4.0 International

15

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language of work or name

English

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publication date

25 March 2010

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published in

PLOS One

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volume

5

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issue

3

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page(s)

e9870

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copyright license

start time

25 March 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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A clinically relevant SCID-hu in vivo model of human multiple myeloma

29 September 2017

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Transforming Growth Factor-Beta in Osteolytic Breast Cancer Bone Metastases

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Cell adhesion-mediated drug resistance (CAM-DR) is associated with activation of NF-κB (RelB/p50) in myeloma cells

29 September 2017

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Antisense inhibition of macrophage inflammatory protein 1-alpha blocks bone destruction in a model of myeloma bone disease

29 September 2017

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Opposite effects of bone morphogenetic protein-2 and transforming growth factor-beta1 on osteoblast differentiation

29 September 2017

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Transforming growth factor beta affects osteoclast differentiation via direct and indirect actions.

29 September 2017

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TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation

29 September 2017

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29 September 2017

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Response to bortezomib is associated to osteoblastic activation in patients with multiple myeloma

27 November 2018

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Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2.

27 November 2018

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Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: a vicious cycle between bone destruction and myeloma expansion

27 November 2018

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27 November 2018

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Ability of myeloma cells to secrete macrophage inflammatory protein (MIP)-1alpha and MIP-1beta correlates with lytic bone lesions in patients with multiple myeloma.

27 November 2018

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Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR).

27 November 2018

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The SCID-rab model: a novel in vivo system for primary human myeloma demonstrating growth of CD138-expressing malignant cells

27 November 2018

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12 December 2020

Transforming growth factor-beta signaling in normal and malignant hematopoiesis

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12 December 2020

Role for macrophage inflammatory protein (MIP)-1alpha and MIP-1beta in the development of osteolytic lesions in multiple myeloma

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12 December 2020

Activation of the bone-derived latent TGF beta complex by isolated osteoclasts

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12 December 2020

Osteoclast synthesis and secretion and activation of latent transforming growth factor beta

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12 December 2020