AKT2 Amplification (Q28445184)

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genetic variant

Amplification

Language	Label	Description	Also known as
English	AKT2 Amplification	genetic variant	Amplification

Statements

Transcript Amplification

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/635

human chromosome 19

genomic assembly

Genome assembly GRCh37

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/635

40736224

genomic assembly

Genome assembly GRCh37

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/635

40791302

genomic assembly

Genome assembly GRCh37

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/635

biological variant of

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/635

positive therapeutic predictor for

vandetanib / everolimus combination therapy

medical condition treated

adenocarcinoma of the lung

determination method

CIViC evidence level C

CIViC 1-star trust rating

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/evidence/1621

Systemic and CNS activity of the RET inhibitor vandetanib combined with the mTOR inhibitor everolimus in KIF5B-RET re-arranged non-small cell lung cancer with brain metastases

Identifiers

CIViC variant ID

1 reference

23 May 2022

https://civic.genome.wustl.edu/links/variants/635

Sitelinks

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