No time to lose--high throughput screening to assess nanomaterial safety (Q28383671)

high-throughput screening

Europe PubMed Central

title

No time to lose--high throughput screening to assess nanomaterial safety (English)

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main subject

nanomaterial

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4

S Pokhrel

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author name string

R Damoiseaux

1

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S George

2

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M Li

3

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Z Ji

5

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B France

6

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T Xia

7

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E Suarez

8

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R Rallo

9

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L Mädler

10

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Y Cohen

11

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E M V Hoek

12

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A Nel

Concept of assessing nanoparticle hazards considering nanoparticle dosemetric and chemical/biological response metrics

13

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language of work or name

English

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publication date

April 2011

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published in

Nanoscale

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volume

3

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issue

4

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page(s)

1345-60

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Toxic potential of materials at the nanolevel

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Effects of phospholipid surfactant on apoptosis induction by respirable quartz and kaolin in NR8383 rat pulmonary macrophages

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Cluster analysis and display of genome-wide expression patterns

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

The adjuvant effect of ambient particulate matter is closely reflected by the particulate oxidant potential

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Oops they did it again! Carbon nanotubes hoax scientists in viability assays

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

The potential environmental impact of engineered nanomaterials

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

In quest of a systematic framework for unifying and defining nanoscience

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

By what means should nanoscaled materials be constructed: molecule, medium, or human?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Ambient ultrafine particles provide a strong adjuvant effect in the secondary immune response: implication for traffic-related asthma flares

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Dispersion and stability optimization of TiO2 nanoparticles in cell culture media.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Fabrication of gold nanoparticles for targeted therapy in pancreatic cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Towards a definition of inorganic nanoparticles from an environmental, health and safety perspective.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Extraction of structure-activity relationship information from high-throughput screening data

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Potential health impact of nanoparticles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Plate-based diversity selection based on empirical HTS data to enhance the number of hits and their chemical diversity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Optically modulated fluorophores for selective fluorescence signal recovery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

High-content screening as a universal tool for fingerprinting of cytotoxicity of nanoparticles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Electrical pulsed stimulation of surfaces homogeneously coated with gold nanoparticles to induce neurite outgrowth of PC12 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Current in vitro methods in nanoparticle risk assessment: limitations and challenges

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

In vivo evaluation of carbon fullerene toxicity using embryonic zebrafish

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Perturbational profiling of nanomaterial biologic activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Toxicity testing in the 21st century: a vision and a strategy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Pro-oxidative DEP chemicals induce heat shock proteins and an unfolding protein response in a bronchial epithelial cell line as determined by DIGE analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Origin and evolution of high throughput screening

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Method for assessment of viability and morphological changes of bacteria in the early stage of colony formation on a simulated natural environment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Inorganic nanotubes: a novel platform for nanofluidics.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Statistical practice in high-throughput screening data analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

An assessment of the utility of the yeast GreenScreen assay in pharmaceutical screening

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Comparison of in vitro and in vivo screening models for androgenic and estrogenic activities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Nano-C60 cytotoxicity is due to lipid peroxidation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Molecular weights of poly(butyl cyanoacrylate) nanoparticles determined by mass spectrometry and size exclusion chromatography

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Homogeneous, bioluminescent protease assays: caspase-3 as a model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Evaluation of the LIVE/DEAD BacLight kit for detection of extremophilic archaea and visualization of microorganisms in environmental hypersaline samples

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Globally distributed object identification for biological knowledgebases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Use of Proteomics to Demonstrate a Hierarchical Oxidative Stress Response to Diesel Exhaust Particle Chemicals in a Macrophage Cell Line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Metal-fume fever from inhaling zinc oxide.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Oxidic nanotubes and nanorods--anisotropic modules for a future nanotechnology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Effect of ABO blood group mismatching on corneal epithelial cells: an in vitro study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Cationic Polystyrene Nanoparticles: Preparation and Characterization of a Model Drug Carrier System for Antisense Oligonucleotides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Fluorescent probes and flow cytometry: new insights into environmental bacteriology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Assessment of the Alamar Blue assay for cellular growth and viability in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Combination of lightweight elements and nanostructured materials for batteries.

2 June 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Quantum dots bearing lectin-functionalized nanoparticles as a platform for in vivo brain imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Semiconductor nanowires for energy conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Noncovalent functionalization of single-walled carbon nanotubes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Advances in patterning materials for 193 nm immersion lithography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Resistance switching in electrodeposited magnetite superlattices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

American Chemical Society meeting. Nanomaterials show signs of toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Research strategies for safety evaluation of nanomaterials. Part VI. Characterization of nanoscale particles for toxicological evaluation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Comparison of scanning electron microscopy, dynamic light scattering and analytical ultracentrifugation for the sizing of poly(butyl cyanoacrylate) nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Is surface roughness a "scapegoat" or a primary factor when defining particle-substrate interactions?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Evaluation of the Vitotox and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

High-throughput reactive oxygen species (ROS) assay: an enabling technology for screening the phototoxic potential of pharmaceutical substances

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

A predictive toxicological paradigm for the safety assessment of nanomaterials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Zinc exposure in Chinese foundry workers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Resveratrol protects primary rat hepatocytes against oxidative stress damage: activation of the Nrf2 transcription factor and augmented activities of antioxidant enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Effect of IFN-gamma on the killing of S. aureus in human whole blood. Assessment of bacterial viability by CFU determination and by a new method using alamarBlue

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Assessment of bacterial endospore viability with fluorescent dyes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Rapid assessment of bacterial viability and vitality by rhodamine 123 and flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

The inhibitory effects of silver nanoparticles, silver ions, and silver chloride colloids on microbial growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

High-throughput screening of silver nanoparticle stability and bacterial inactivation in aquatic media: influence of specific ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Stability, bioavailability, and bacterial toxicity of ZnO and iron-doped ZnO nanoparticles in aquatic media

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Enhanced HTS hit selection via a local hit rate analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Improved method to disperse nanoparticles for in vitro and in vivo investigation of toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

A systematic nomenclature for codifying engineered nanostructures

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Carbon Nanotubes--the Route Toward Applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

The use of monochlorobimane to determine hepatic GSH levels and synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

Growth of Ultrafine Single Crystalline WO3Nanoparticles Using Flame Spray Pyrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0NR00618A

VITOTOX bacterial genotoxicity and toxicity test for the rapid screening of chemicals.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980675

Nanotechnology. Can high-speed tests sort out which nanomaterials are safe?

27 November 2018

1 reference

12 December 2020

Colloidal GaAs quantum wires: solution-liquid-solid synthesis and quantum-confinement studies

1 reference

12 December 2020

Risks in new drug development: approval success rates for investigational drugs

1 reference

12 December 2020

Proposed minimum characterization parameters for studies on food and food-related nanomaterials

1 reference

12 December 2020

1 reference

12 December 2020

Determination of nitric oxide generation in mammalian neurons using dichlorofluorescin diacetate and flow cytometry

1 reference

12 December 2020

LIVE/DEAD BacLight : application of a new rapid staining method for direct enumeration of viable and total bacteria in drinking water

1 reference

12 December 2020

Development of a high-throughput in vitro bioassay to assess potencies of progestagenic compounds using chinese hamster ovary cells stably transfected with the human progesterone receptor and a luciferase reporter system

1 reference

12 December 2020

Nonaqueous Sol–Gel Routes to Metal Oxide Nanoparticles

1 reference

12 December 2020

How meaningful are the results of nanotoxicity studies in the absence of adequate material characterization?

1 reference

12 December 2020

Inhibition of the P-glycoprotein- and multidrug resistance protein-mediated efflux of anthracyclines and calceinacetoxymethyl ester by PAK-104P

1 reference

12 December 2020

Putting nature back into drug discovery

1 reference

12 December 2020