A cluster of negative charges at the amino terminal tail of CFTR regulates ATP-dependent channel gating (Q28361675)

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H L Ji

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A P Naren

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K L Kirk

Walker mutations reveal loose relationship between catalytic and channel-gating activities of purified CFTR (cystic fibrosis transmembrane conductance regulator)

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language of work or name

English

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publication date

15 October 2001

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published in

Journal of Physiology

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volume

536

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issue

Pt 2

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page(s)

459-70

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cites work

1 reference

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Crystal structure of the ATP-binding subunit of an ABC transporter

20 March 2017

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Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms

20 March 2017

1 reference

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Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

20 March 2017

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Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport

20 March 2017

1 reference

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Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domains

20 March 2017

1 reference

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Severed molecules functionally define the boundaries of the cystic fibrosis transmembrane conductance regulator's NH(2)-terminal nucleotide binding domain

29 September 2017

1 reference

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Regulation of CFTR Cl- channel gating by ATP binding and hydrolysis

29 September 2017

1 reference

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Syntaxin 1A is expressed in airway epithelial cells, where it modulates CFTR Cl(-) currents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2278861

Syntaxin 1A inhibits CFTR chloride channels by means of domain-specific protein-protein interactions

29 September 2017

1 reference

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Cystic fibrosis: genotypic and phenotypic variations

29 September 2017

1 reference

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CFTR: the nucleotide binding folds regulate the accessibility and stability of the activated state

29 September 2017

1 reference

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Cystic fibrosis heterozygote resistance to cholera toxin in the cystic fibrosis mouse model

29 September 2017

1 reference

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Effect of ATP concentration on CFTR Cl- channels: a kinetic analysis of channel regulation

29 September 2017

1 reference

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Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis

29 September 2017

1 reference

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Chloride impermeability in cystic fibrosis

29 September 2017

1 reference

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Defective function of the cystic fibrosis-causing missense mutation G551D is recovered by genistein

29 September 2017

1 reference

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Mutations in the cystic fibrosis gene in men with congenital bilateral absence of the vas deferens

2 June 2018

1 reference

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Mutations in CFTR associated with mild-disease-form Cl- channels with altered pore properties.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2278861

Conformational states of CFTR associated with channel gating: the role ATP binding and hydrolysis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2278861

The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2278861

Early bacteriologic, immunologic, and clinical courses of young infants with cystic fibrosis identified by neonatal screening

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2278861

Nucleoside triphosphates are required to open the CFTR chloride channel.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2278861

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2278861

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2278861

Coupling of CFTR Cl- channel gating to an ATP hydrolysis cycle

2 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2001.0459C.XD

Dibasic protein kinase A sites regulate bursting rate and nucleotide sensitivity of the cystic fibrosis transmembrane conductance regulator chloride channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2001.0459C.XD

CFTR chloride channel regulation by an interdomain interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2001.0459C.XD

Expression and characterization of the NBD1-R domain region of CFTR: evidence for subunit-subunit interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2001.0459C.XD

Syntaxin 1A inhibits regulated CFTR trafficking in xenopus oocytes.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2278861

Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2278861

CFTR activation: additive effects of stimulatory and inhibitory phosphorylation sites in the R domain.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2278861

The non-hydrolytic pathway of cystic fibrosis transmembrane conductance regulator ion channel gating

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11600681

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The CFTR chloride channel: nucleotide interactions and temperature-dependent gating

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11600681

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cystic fibrosis transmembrane conductance regulator: the purified NBF1+R protein interacts with the purified NBF2 domain to form a stable NBF1+R/NBF2 complex while inducing a conformational change transmitted to the C-terminal region

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11600681