Mutations lowering the phosphatase activity of HPr kinase/phosphatase switch off carbon metabolism (Q28345070)

2

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I Mijakovic

3

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S Fieulaine

4

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V Dossonnet

5

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I Martin-Verstraete

6

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S Nessler

7

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J Deutscher

X-ray structure of HPr kinase: a bacterial protein kinase with a P-loop nucleotide-binding domain

8

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language of work or name

English

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publication date

1 August 2001

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published in

The EMBO Journal

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volume

20

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page(s)

3928-37

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issue

15

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cites work

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Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase from Salmonella typhimurium determined to 2.3 A resolution,

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Crystal structure of a trapped phosphoenzyme during a catalytic reaction

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The crystal structure of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase reveals distinct domain homologies

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Cascade control of Escherichia coli glutamine synthetase. Purification and properties of PII uridylyltransferase and uridylyl-removing enzyme

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Loss of protein kinase-catalyzed phosphorylation of HPr, a phosphocarrier protein of the phosphotransferase system, by mutation of the ptsH gene confers catabolite repression resistance to several catabolic genes of Bacillus subtilis

20 March 2017

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Regulation of carbon catabolism in Bacillus species.

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Phosphatase activity of histidine kinase EnvZ without kinase catalytic domain.

29 September 2017

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Phosphorylation of HPr by the bifunctional HPr Kinase/P-ser-HPr phosphatase from Lactobacillus casei controls catabolite repression and inducer exclusion but not inducer expulsion

29 September 2017

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Characterization of an HPr kinase mutant of Staphylococcus xylosus

29 September 2017

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Evaluation and characterization of catabolite-responsive elements (cre) of Bacillus subtilis

29 September 2017

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The HPr kinase from Bacillus subtilis is a homo-oligomeric enzyme which exhibits strong positive cooperativity for nucleotide and fructose 1,6-bisphosphate binding

29 September 2017

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Catabolite regulation of the pta gene as part of carbon flow pathways in Bacillus subtilis.

29 September 2017

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Cloning, characterization and expression of a bifunctional fructose-6-phosphate, 2-kinase/fructose-2,6-bisphosphatase from potato.

29 September 2017

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Phosphorylation of HPr and Crh by HprK, early steps in the catabolite repression signalling pathway for the Bacillus subtilis levanase operon.

29 September 2017

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trans-acting factors affecting carbon catabolite repression of the hut operon in Bacillus subtilis

29 September 2017

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New protein kinase and protein phosphatase families mediate signal transduction in bacterial catabolite repression

29 September 2017

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The two opposing activities of adenylyl transferase reside in distinct homologous domains, with intramolecular signal transduction

29 September 2017

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The Bacillus subtilis crh gene encodes a HPr-like protein involved in carbon catabolite repression

29 September 2017

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Regulation of sugar uptake via the phosphoenolpyruvate-dependent phosphotransferase systems in Bacillus subtilis and Lactococcus lactis is mediated by ATP-dependent phosphorylation of seryl residue 46 in HPr

29 September 2017

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Specific recognition of the Bacillus subtilis gnt cis-acting catabolite-responsive element by a protein complex formed between CcpA and seryl-phosphorylated HPr.

29 September 2017

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Cooperative binding of lactose and the phosphorylated phosphocarrier protein HPr(Ser-P) to the lactose/H+ symport permease of Lactobacillus brevis

29 September 2017

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Use of 31P nuclear magnetic resonance spectroscopy and 14C fluorography in studies of glycolysis and regulation of pyruvate kinase in Streptococcus lactis.

29 September 2017

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ATP-dependent protein kinase-catalyzed phosphorylation of a seryl residue in HPr, a phosphate carrier protein of the phosphotransferase system in Streptococcus pyogenes

29 September 2017

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Induction and metabolite regulation of levanase synthesis in Bacillus subtilis

29 September 2017

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Site-directed mutagenesis of a catabolite repression operator sequence in Bacillus subtilis

29 September 2017

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Isocitrate dehydrogenase kinase/phosphatase: aceK alleles that express kinase but not phosphatase activity

29 September 2017

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Adenylylation/Deadenylylation Control of the Glutamine Synthetase of Rhodopseudomonas capsulata

29 September 2017

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Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis

29 September 2017

1 reference

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A vector for systematic gene inactivation in Bacillus subtilis

2 June 2018

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Catabolite repression of alpha-amylase gene expression in Bacillus subtilis involves a trans-acting gene product homologous to the Escherichia coli lacl and galR repressors

2 June 2018

1 reference

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Bacterial phosphoenolpyruvate-dependent phosphotransferase system: P-Ser-HPr and its possible regulatory function?

2 June 2018

1 reference

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Induction of the Bacillus subtilis ptsGHI operon by glucose is controlled by a novel antiterminator, GlcT.

27 November 2018

1 reference

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Catabolite repression mediated by the CcpA protein in Bacillus subtilis: novel modes of regulation revealed by whole-genome analyses

27 November 2018

1 reference

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The hprK gene of Enterococcus faecalis encodes a novel bifunctional enzyme: the HPr kinase/phosphatase.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149165

A novel protein kinase that controls carbon catabolite repression in bacteria

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=149165

Locations of the regulatory sites for isocitrate dehydrogenase kinase/phosphatase

27 November 2018

1 reference

12 December 2020

Protein kinase-dependent HPr/CcpA interaction links glycolytic activity to carbon catabolite repression in gram-positive bacteria

1 reference

12 December 2020

Enzyme I and HPr from Lactobacillus casei: their role in sugar transport, carbon catabolite repression and inducer exclusion

1 reference

12 December 2020

The catabolite control protein CcpA controls ammonium assimilation in Bacillus subtilis

1 reference

12 December 2020

A protein with kinase and phosphatase activities involved in regulation of tricarboxylic acid cycle

1 reference

12 December 2020

Characterization of phosphorylated histidine-containing protein (HPr) of the bacterial phosphoenolpyruvate:sugar phosphotransferase system

1 reference

12 December 2020

Streptococcal phosphoenolpyruvate-sugar phosphotransferase system: amino acid sequence and site of ATP-dependent phosphorylation of HPr

1 reference

12 December 2020

Site-directed mutagenesis with the ptsH gene of Bacillus subtilis. Isolation and characterization of heat-stable proteins altered at the ATP-dependent regulatory phosphorylation site

1 reference

12 December 2020

Binding of the catabolite repressor protein CcpA to its DNA target is regulated by phosphorylation of its corepressor HPr

1 reference

12 December 2020

Replacement of isoleucine-47 by threonine in the HPr protein of Streptococcus salivarius abrogates the preferential metabolism of glucose and fructose over lactose and melibiose but does not prevent the phosphorylation of HPr on serine-46

1 reference

12 December 2020

Phosphorylation of either crh or HPr mediates binding of CcpA to the bacillus subtilis xyn cre and catabolite repression of the xyn operon

1 reference

12 December 2020