The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis (Q28344804)

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English	The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis	scientific article

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scholarly article

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The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis (English)

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tumor angiogenesis

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6

object named as

Michael Detmar

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author name string

Donald R Senger

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Carole A Perruzzi

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Michael Streit

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Victor E Koteliansky

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Antonin R de Fougerolles

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language of work or name

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publication date

January 2002

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The American Journal of Pathology

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160

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195-204

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1

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Integrin signaling

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20 March 2017

Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins

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20 March 2017

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

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20 March 2017

Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins

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20 March 2017

The MAPK signaling cascade

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20 March 2017

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis

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20 March 2017

Integrins: versatility, modulation, and signaling in cell adhesion

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20 March 2017

Glomerular epithelial and mesangial cells differentially modulate the binding specificities of VLA-1 and VLA-2

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867136

20 March 2017

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

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7 April 2017

Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

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7 April 2017

Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin

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29 September 2017

Regulation of inflammation by collagen-binding integrins alpha1beta1 and alpha2beta1 in models of hypersensitivity and arthritis

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29 September 2017

Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization

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29 September 2017

Expression of vascular endothelial growth factor induces an invasive phenotype in human squamous cell carcinomas

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29 September 2017

Thrombospondin-2: a potent endogenous inhibitor of tumor growth and angiogenesis

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29 September 2017

Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase

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29 September 2017

Confluence of vascular endothelial cells induces cell cycle exit by inhibiting p42/p44 mitogen-activated protein kinase activity

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29 September 2017

Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.

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29 September 2017

Growth factor activation of MAP kinase requires cell adhesion.

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29 September 2017

Trans-dominant inhibition of integrin function.

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29 September 2017

Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

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29 September 2017

Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867136

29 September 2017

Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.

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29 September 2017

Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth.

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29 September 2017

The role of vascular endothelial growth factor in pathological angiogenesis

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29 September 2017

Vascular permeability factor (VPF, VEGF) in tumor biology

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29 September 2017

Endothelial receptor tyrosine kinases involved in angiogenesis.

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29 September 2017

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867136

29 September 2017

Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase

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2 June 2018

Anchorage-dependent regulation of the mitogen-activated protein kinase cascade by growth factors is supported by a variety of integrin alpha chains

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1867136

2 June 2018

Regulation of vascular endothelial growth factor by oxygen in a model of retinopathy of prematurity.

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2 June 2018

An antagonist of integrin alpha v beta 3 prevents maturation of blood vessels during embryonic neovascularization

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2 June 2018

Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

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2 June 2018

Purification and NH2-terminal amino acid sequence of guinea pig tumor-secreted vascular permeability factor.

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2 June 2018

A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin, and fibroblast growth factor

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2 June 2018

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

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Integrins, adhesion and apoptosis.

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27 November 2018

Nitric oxide is an upstream signal of vascular endothelial growth factor-induced extracellular signal-regulated kinase1/2 activation in postcapillary endothelium

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7 January 2021

Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor

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7 January 2021

VLA-2 mediates the interaction of collagen with endothelium during in vitro vascular tube formation

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7 January 2021

An alpha 2 beta 1 integrin-dependent pinocytic mechanism involving intracellular vacuole formation and coalescence regulates capillary lumen and tube formation in three-dimensional collagen matrix

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7 January 2021

Definition of Two Angiogenic Pathways by Distinct alpha(v) Integrins

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A mechanism for modulation of cellular responses to VEGF: activation of the integrins

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Targeted mutations in integrins and their ligands: their implications for vascular biology

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