The cytochrome P450 4 (CYP4) family (Q28305817)

Chlorophenoxyacid herbicides induce microsomal cytochrome P-450 IVA1 (P-452) in rat liver

Europe PubMed Central

title

The cytochrome P450 4 (CYP4) family (English)

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author name string

A E Simpson

series ordinal

1

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language of work or name

English

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publication date

March 1997

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published in

General Pharmacology

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volume

28

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page(s)

351-9

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issue

3

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cites work

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Immunochemical study on the contribution of hypolipidaemic-induced cytochrome P-452 to the metabolism of lauric acid and arachidonic acid

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Induction of cytochrome P450III and P450IV family proteins in streptozotocin-induced diabetes

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Localization and differential induction of cytochrome P450IVA and acyl-CoA oxidase in rat liver

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Differential tissue-specific expression and induction of cytochrome P450IVA1 and acyl-CoA oxidase

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Induction of acyl-CoA oxidase and cytochrome P450IVA1 RNA in rat primary hepatocyte culture by peroxisome proliferators

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Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs

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Hepatic peroxisome proliferation in rodents and its significance for humans

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Lactational transfer of 2,4,5,2',4',5'-hexachlorobiphenyl but not 3,4,3',4'-tetrachlorobiphenyl, induces neonatal CYP4A1

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Transplacental transfer of polychlorinated biphenyls induces simultaneously the expression of P450 isoenzymes and the protooncogenes c-Ha-ras and c-raf

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Alterations in rat hepatic drug metabolism during pregnancy and lactation

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Inducibility and functionality of rat embryonic/foetal cytochrome P-450: A study of differentiating limb-bud and mid-brain cells in vitro

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Zonation of cytochrome P450 isozyme expression and induction in rat liver

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Identification of a new P450 subfamily, CYP4F1, expressed in rat hepatic tumors

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7 January 2021

Differential splicing in the 3' non-coding region of rat cytochrome P-452 (P450 IVA1) mRNA.

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Peroxisome proliferation and induction of peroxisomal enzymes in mouse and rat liver by dehydroepiandrosterone feeding

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Cluster of cytochrome P450 genes on the X chromosome of Drosophila melanogaster.

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Molecular analysis of a cytochrome P450 gene of family 4 on the Drosophila X chromosome.

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Comparative aspects of the mammalian cytochrome P450 IV gene family

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PPAR: a mediator of peroxisome proliferator action

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Expression of xenobiotic-metabolizing cytochrome P450 forms in human adult and fetal liver

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7 January 2021

26 CYP4A subfamily: Functional analysis by immunohistochemistry and in Situ hybridization

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Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: developmental and hormonal regulation in liver and kidney

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Purification and NH2-terminal sequence of cytochrome P-450 from kidney microsomes of untreated male rats

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7 January 2021

Characterization of three cytochrome P450s purified from renal microsomes of untreated male rats and comparison with human renal cytochrome P450.

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7 January 2021

Induction and regulation of cytochrome P450 K-5 (lauric acid hydroxylase) in rat renal microsomes by starvation

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7 January 2021

Expression and inducibility of cytochrome P450 proteins belonging to families 2,3 and 4 in the rabbit aorta

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Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

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The retinoid X receptor enhances the function of the peroxisome proliferator activated receptor

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Isolation of preferentially expressed genes in the kidneys of hypertensive rats

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7 January 2021

Chlorotrifluoroethylene trimer and tetramer are inducers of the CYP4A subfamily

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7 January 2021

Cloning and expression of three rabbit kidney cDNAs encoding lauric acid omega-hydroxylases

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7 January 2021

Purification and cDNA cloning of human liver CYP4A fatty acid omega-hydroxylase

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7 January 2021

Purification and NH2-terminal amino acid sequences of human and rat kidney fatty acid omega-hydroxylases

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7 January 2021

cDNA cloning of three new forms of rat brain cytochrome P450 belonging to the CYP4F subfamily

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7 January 2021

Purification and characterization of two forms of cytochrome P-450 with omega-hydroxylase activities toward prostaglandin A and fatty acids from rabbit liver microsomes

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7 January 2021

The rat clofibrate-inducible CYP4A gene subfamily. I. Complete intron and exon sequence of the CYP4A1 and CYP4A2 genes, unique exon organization, and identification of a conserved 19-bp upstream element

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The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes

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7 January 2021

Isolation of a new form of cytochrome P-450 with prostaglandin A and fatty acid omega-hydroxylase activities from rabbit kidney cortex microsomes

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7 January 2021

Renal microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid

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7 January 2021

On the mechanism of induction of microsomal cytochrome P450IVA1 and peroxisome proliferation in rat liver by clofibrate

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7 January 2021

Characterization of a rabbit gene encoding a clofibrate-inducible fatty acid omega-hydroxylase: CYP4A6.

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Purification and properties of pregnancy-inducible rabbit lung cytochrome P-450 prostaglandin omega-hydroxylase

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7 January 2021

The distribution of different forms of cytochrome P-450 in human liver

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Effects of high-fat diets on hepatic fatty acid oxidation in the rat Isolation of rat liver peroxisomes by vertical-rotor centrifugation by using a self-generated, iso-osmotic, Percoll gradient

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7 January 2021

The P450 gene superfamily: recommended nomenclature.

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7 January 2021

P450 gene nomenclature based on evolution.

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Developmental aspects of the hepatic cytochrome P450 monooxygenase system

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The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature

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Identification of a new P450 expressed in human lung: complete cDNA sequence, cDNA-directed expression, and chromosome mapping

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7 January 2021

Growth hormone mediates zone-specific gene expression in liver

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Roles of renal cytochrome P450-dependent arachidonic acid metabolites in hypertension

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Immunoelectron microscopic localization of cytochrome P-450 isoenzyme CYP4A1 in liver, ileum and kidney of nafenopin treated male rats

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7 January 2021

Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens

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Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans

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Induction of hepatic microsomal CYP4A activity and of peroxisomal beta-oxidation by two non-steroidal anti-inflammatory drugs

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7 January 2021

Expression of rabbit cytochromes P4504A which catalyze the omega-hydroxylation of arachidonic acid, fatty acids, and prostaglandins.

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7 January 2021

Suppression of clofibrate-induction of peroxisomal and microsomal fatty acid-oxidizing enzymes by growth hormone and thyroid hormone in primary cultures of rat hepatocytes

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Renal cytochrome P450-related arachidonate metabolite inhibits (Na+ + K+)ATPase

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Cytochrome P450-dependent arachidonic acid metabolism in human kidney

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Diversity of cytochrome P450 genes in the mosquito, Anopheles albimanus

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Role of hepatic and renal cytochrome P-450 IVA1 in the metabolism of lipid substrates

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Co-induction of microsomal cytochrome P-452 and the peroxisomal fatty acid β-oxidation pathway in the rat by clofibrate and di-(2-ethylhexyl)phthalate

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Translactational induction of CYP4A expression in 10.5-day neonatal rats by the hypolipidemic drug clofibrate

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The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking sequence of the rat acyl CoA oxidase gene

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