Acamprosate produces its anti-relapse effects via calcium (Q28299533)

1

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Valentina Vengeliene

2

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Bernd Jandeleit

3

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Wolf-Nicolas Fischer

4

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Kent Grindstaff

5

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Xuexiang Zhang

6

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Mark A Gallop

7

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Elena V Krstew

8

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Andrew J Lawrence

9

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Falk Kiefer

Acamprosate for alcohol dependence

10

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language of work or name

English

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publication date

March 2014

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published in

Neuropsychopharmacology

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volume

39

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issue

4

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page(s)

783-91

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cites work

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Acamprosate (calcium acetylhomotaurinate) enhances the N-methyl-D-aspartate component of excitatory neurotransmission in rat hippocampal CA1 neurons in vitro

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A homotaurine derivative reduces the voluntary intake of ethanol by rats: are cerebral GABA receptors involved?

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Glycine receptors in the nucleus accumbens involved in the ethanol intake-reducing effect of acamprosate

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Glycine receptors involved in acamprosate's modulation of accumbal dopamine levels: an in vivo microdialysis study

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The acute anti-craving effect of acamprosate in alcohol-preferring rats is associated with modulation of the mesolimbic dopamine system

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Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors

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Chronic acamprosate eliminates the alcohol deprivation effect while having limited effects on baseline responding for ethanol in rats.

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Comparing and combining naltrexone and acamprosate in relapse prevention of alcoholism: a double-blind, placebo-controlled study

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The glycine reuptake inhibitor Org24598 and acamprosate reduce ethanol intake in the rat; tolerance development to acamprosate but not to Org24598.

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Extending the treatment options in alcohol dependence: a randomized controlled study of as-needed nalmefene

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Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: hippocampus and cortex

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Acamprosate (calciumacetylhomotaurinate) decreases postsynaptic potentials in the rat neocortex: possible involvement of excitatory amino acid receptors.

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Expression of N-methyl-D-aspartate receptor subunit mRNAs in the human brain: striatum and globus pallidus

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Acamprosate and alcohol: I. Effects on alcohol intake following alcohol deprivation in the rat

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Acamprosate and alcohol: II. Effects on alcohol withdrawal in the rat

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Experimental evidence in the treatment of alcoholism by intensive calcium therapy

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Physicochemical, pharmacological and pharmacokinetic study of a new GABAergic compound, calcium acetylhomotaurinate

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Identifiers

DOI

10.1038/NPP.2013.264

1 reference

Dimensions Publication ID

1027481743

0 references

1 reference

1 reference

PubMed publication ID

24081303

1 reference