Connexin43 functions as a novel interacting partner of heat shock cognate protein 70 (Q28298986)

1

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Ping Dai

2

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Yoshinori Harada

3

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Hitoshi Hino

4

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Fujiko Tsukahara

5

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Yoshiro Maru

6

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Eigo Otsuji

7

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Tetsuro Takamatsu

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

8

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language of work or name

English

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publication date

2013

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published in

Scientific Reports

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volume

3

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page(s)

2719

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copyright license

start time

23 September 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70

20 March 2017

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SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

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p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

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The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein

20 March 2017

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Characterization of the thermotolerant cell. II. Effects on the intracellular distribution of heat-shock protein 70, intermediate filaments, and small nuclear ribonucleoprotein complexes

20 March 2017

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Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytes

20 March 2017

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Drebrin is a novel connexin-43 binding partner that links gap junctions to the submembrane cytoskeleton

20 March 2017

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The gap junction-independent tumor-suppressing effect of connexin 43

20 March 2017

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Hsc70 regulates accumulation of cyclin D1 and cyclin D1-dependent protein kinase

20 March 2017

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73-kDa heat shock cognate protein interacts directly with P27Kip1, a cyclin-dependent kinase inhibitor, during G1/S transition

20 March 2017

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Comprehensive review on the HSC70 functions, interactions with related molecules and involvement in clinical diseases and therapeutic potential

20 March 2017

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Aberrant expression and localization of connexin43 and connexin30 in a rat glioma cell line.

29 September 2017

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Participation of the chaperone Hsc70 in the trafficking and functional expression of ASIC2 in glioma cells

29 September 2017

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Cx43 mediates TGF-beta signaling through competitive Smads binding to microtubules

29 September 2017

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Connexins act as tumor suppressors in three-dimensional mammary cell organoids by regulating differentiation and angiogenesis

29 September 2017

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Multiphoton excitation-evoked chromophore-assisted laser inactivation using green fluorescent protein

29 September 2017

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Gap junctions and the propagation of cell survival and cell death signals

29 September 2017

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Altered expression of Cx43 in astrocytic tumors

29 September 2017

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Beyond the gap: functions of unpaired connexon channels

29 September 2017

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The regulatory role of the C-terminal domain of connexin43.

29 September 2017

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Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication

29 September 2017

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Dominant-negative connexin43-EGFP inhibits calcium-transient synchronization of primary neonatal rat cardiomyocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Gap junction protein connexin-43 interacts directly with microtubules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Interaction of c-Src with gap junction protein connexin-43. Role in the regulation of cell-cell communication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Aberrant expression of photoreceptor-specific calcium-binding protein (recoverin) in cancer cell lines.

29 September 2017

1 reference

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p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Suppression of human prostate cancer cell growth by forced expression of connexin genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Nuclear translocation of stress protein Hsc70 during S phase in rat C6 glioma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Tyrosine phosphorylation of connexin 43 by v-Src is mediated by SH2 and SH3 domain interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Connexins, connexons, and intercellular communication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

The gap junction communication channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Increased expression of co-chaperone HOP with HSP90 and HSC70 and complex formation in human colonic carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Cooperation of salivary protein histatin 3 with heat shock cognate protein 70 relative to the G1/S transition in human gingival fibroblasts

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Reduced connexin43 expression in high-grade human brain glioma cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Gap-junction protein gene suppresses tumorigenicity

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Reduced expression of connexin-43 and functional gap junction coupling in human gliomas

2 June 2018

1 reference

Growth inhibition of transformed cells correlates with their junctional communication with normal cells.

21 January 2018

1 reference

The tumor-suppressive function of Connexin43 in keratinocytes is mediated in part via interaction with caveolin-1.

21 January 2018

1 reference

Dual functions for connexins: Cx43 regulates growth independently of gap junction formation

21 January 2018

1 reference

p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70.

21 January 2018

1 reference

Generation of reentrant arrhythmias by dominant-negative inhibition of connexin43 in rat cultured myocyte monolayers.

21 January 2018

1 reference

Identification of novel nuclear export and nuclear localization-related signals in human heat shock cognate protein 70.

21 January 2018

1 reference

Mutations in the second extracellular region of connexin 43 prevent localization to the plasma membrane, but do not affect its ability to suppress cell growth.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43).

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779846

The carboxy-tail of connexin-43 localizes to the nucleus and inhibits cell growth

27 November 2018

1 reference

12 December 2020

A novel route for connexin 43 to inhibit cell proliferation: negative regulation of S-phase kinase-associated protein (Skp 2)

1 reference

12 December 2020

CBP as a transcriptional coactivator of c-Myb

1 reference

12 December 2020

Different constitutive heat shock protein 70 expression during proliferation and differentiation of rat C6 glioma cells

1 reference

12 December 2020

Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP02719

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Dimensions Publication ID

1028615037

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1 reference

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PubMed publication ID

24056538

1 reference