HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability (Q28294885)

1

0 references

Louise J Barber

2

0 references

Allison J Clark

3

0 references

Julie S Martin

4

0 references

Jordan D Ward

5

0 references

Simon J Boulton

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

6

0 references

language of work or name

English

0 references

publication date

April 2007

0 references

published in

Nature Cell Biology

0 references

volume

9

0 references

issue

4

0 references

page(s)

391-401

0 references

cites work

1 reference

Cell-cycle checkpoints and cancer

21 April 2017

1 reference

The DNA damage response: putting checkpoints in perspective

21 April 2017

1 reference

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

21 April 2017

1 reference

The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo

21 April 2017

1 reference

C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein

21 April 2017

1 reference

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

21 April 2017

1 reference

Human claspin is required for replication checkpoint control

21 April 2017

1 reference

MDC1 is required for the intra-S-phase DNA damage checkpoint

21 April 2017

1 reference

MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways

21 April 2017

1 reference

MDC1 is a mediator of the mammalian DNA damage checkpoint

21 April 2017

1 reference

Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems

21 April 2017

1 reference

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

21 April 2017

1 reference

The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

21 April 2017

1 reference

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

21 April 2017

1 reference

Chk1 is required to maintain claspin stability

21 April 2017

1 reference

Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

21 April 2017

1 reference

A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome

21 April 2017

1 reference

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

21 April 2017

1 reference

Human CLK2 links cell cycle progression, apoptosis, and telomere length regulation

21 April 2017

1 reference

21 April 2017

1 reference

Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint

21 April 2017

1 reference

gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes

21 April 2017

1 reference

The Fanconi Anemia/BRCA pathway: new faces in the crowd

21 January 2018

1 reference

Circadian clock genes as modulators of sensitivity to genotoxic stress.

21 January 2018

1 reference

The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells

21 January 2018

1 reference

The Neurospora checkpoint kinase 2: a regulatory link between the circadian and cell cycles

21 January 2018

1 reference

Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans

21 January 2018

1 reference

A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites.

21 January 2018

1 reference

Human TopBP1 ensures genome integrity during normal S phase

21 January 2018

1 reference

Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage

21 January 2018

1 reference

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

21 January 2018

1 reference

Chk1 is haploinsufficient for multiple functions critical to tumor suppression

21 January 2018

1 reference

ATR couples FANCD2 monoubiquitination to the DNA-damage response

21 January 2018

1 reference

Nbs1 is required for ATR-dependent phosphorylation events

21 January 2018

1 reference

Double-strand-break-induced homologous recombination in mammalian cells

21 January 2018

1 reference

Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks

21 January 2018

1 reference

Checking on DNA damage in S phase

21 January 2018

1 reference

Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage

21 January 2018

1 reference

Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway.

21 January 2018

1 reference

The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability

21 January 2018

1 reference

Temporally coordinated assembly and disassembly of replication factories in the absence of DNA synthesis

21 January 2018

1 reference

Mechanisms involved in regulating DNA replication origins during the cell cycle and in response to DNA damage.

21 January 2018

1 reference

7 January 2021

Inhibition of DNA synthesis by ionizing radiation: a marker for an S-phase checkpoint

1 reference

7 January 2021

Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway

1 reference

7 January 2021

C. elegans FANCD2 responds to replication stress and functions in interstrand cross-link repair

1 reference

7 January 2021

Identifiers

DOI

10.1038/NCB1555

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

4775072

1004344850

0 references

4775072

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference