In vivo reprogramming of adult pancreatic exocrine cells to beta-cells (Q28292190)

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Juliana Brown

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Andrew Kanarek

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Jayaraj Rajagopal

https://api.crossref.org/works/10.1038%2FNATURE07314

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language of work or name

English

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publication date

2 October 2008

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published in

Nature

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volume

455

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page(s)

627-32

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issue

7213

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7 January 2021

Nuclear reprogramming and pluripotency

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Hematopoiesis: an evolving paradigm for stem cell biology

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Metaplasia and transdifferentiation: from pure biology to the clinic

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Plasticity and reprogramming of differentiated cells in amphibian regeneration

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Transdetermination in Cells

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From nuclear transfer to nuclear reprogramming: the reversal of cell differentiation

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

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Induced pluripotent stem cell lines derived from human somatic cells

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Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells

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In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

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Reprogramming of human somatic cells to pluripotency with defined factors

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MyoD converts primary dermal fibroblasts, chondroblasts, smooth muscle, and retinal pigmented epithelial cells into striated mononucleated myoblasts and multinucleated myotubes

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Molecular basis of transdifferentiation of pancreas to liver

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Stepwise reprogramming of B cells into macrophages

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Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors

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fgf20 is essential for initiating zebrafish fin regeneration.

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Cell differentiation and cell fate during urodele tail and limb regeneration

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A multipotent progenitor domain guides pancreatic organogenesis.

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Genes, Signals, and Lineages in Pancreas Development

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Gene regulatory factors in pancreatic development

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7 January 2021

In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells

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7 January 2021

Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells

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Comparison of adenoviral and adeno-associated viral vectors for pancreatic gene delivery in vivo

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Adenovirus transduction is required for the correction of diabetes using Pdx-1 or Neurogenin-3 in the liver

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7 January 2021

Role of VEGF-A in vascularization of pancreatic islets

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7 January 2021

EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets

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7 January 2021

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

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7 January 2021

PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance

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Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis.

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7 January 2021

Pancreatic acinar-to-beta cell transdifferentiation in vitro

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7 January 2021

Generation of insulin-secreting cells from pancreatic acinar cells of animal models of type 1 diabetes.

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7 January 2021

Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells.

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7 January 2021

Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3

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https://api.crossref.org/works/10.1038%2FNATURE07314

7 January 2021

Proendocrine genes coordinate the pancreatic islet differentiation program in vitro

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https://api.crossref.org/works/10.1038%2FNATURE07314

7 January 2021

Endocrine precursor cells from mouse islets are not generated by epithelial-to-mesenchymal transition of mature beta cells

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https://api.crossref.org/works/10.1038%2FNATURE07314

7 January 2021

Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells

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7 January 2021

Gene activation in somatic nuclei after injection into amphibian oocytes / E. M. De Robertis, J. B. Gurdon. - (1977)

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7 January 2021

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

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7 January 2021

Identifiers

DOI

10.1038/NATURE07314

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

131777

ADS bibcode

2008Natur.455..627Z

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1005774015

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131777

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference