DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer (Q28287769)

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27 February 2020

title

DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer (English)

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27 February 2020

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1

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27 February 2020

Claire Palles

3

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27 February 2020

Enric Domingo

4

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27 February 2020

Jenny Taylor

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27 February 2020

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Ian P M Tomlinson

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27 February 2020

author name string

Sarah E W Briggs

2

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27 February 2020

Stephen J Kearsey

5

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27 February 2020

Jonathon M Grimes

6

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27 February 2020

Maggie Gorman

7

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27 February 2020

Lynn Martin

8

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27 February 2020

Kimberley M Howarth

9

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27 February 2020

Shirley V Hodgson

10

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27 February 2020

Kulvinder Kaur

12

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27 February 2020

NSECG Collaborators

11

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language of work or name

English

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publication date

24 March 2013

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27 February 2020

published in

Human Molecular Genetics

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27 February 2020

volume

22

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27 February 2020

page(s)

2820-2828

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27 February 2020

issue

14

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Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

27 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Comprehensive genomic characterization of squamous cell lung cancers

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Comprehensive molecular characterization of human colon and rectal cancer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Division of labor at the eukaryotic replication fork

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Yeast DNA polymerase epsilon participates in leading-strand DNA replication

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

20 March 2017

The 3' 5' exonucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Recurrent R-spondin fusions in colon cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Endometrial carcinoma: molecular alterations involved in tumor development and progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Mutator suppression and escape from replication error-induced extinction in yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Microsatellite instability and loss of heterozygosity at chromosomal location 18q: prospective evaluation of biomarkers for stages II and III colon cancer--a study of CALGB 9581 and 89803.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Genome-wide model for the normal eukaryotic DNA replication fork.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

29 September 2017

DNA replication fidelity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase delta

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690967

Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDT131

Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDT131

Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice

21 January 2018

1 reference

12 December 2020

Hereditary colorectal cancer

1 reference

12 December 2020

Frequent hypermethylation of MLH1 promoter in normal endometrium of patients with endometrial cancers

1 reference

12 December 2020

Amino acid changes coded by bacteriophage T4 DNA polymerase mutator mutants. Relating structure to function

1 reference

12 December 2020

MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDT131

2 references

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27 February 2020

1 reference

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27 February 2020

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