The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis (Q28287224)

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English	The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis	scientific article

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scholarly article

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The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

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Nikolay V. Dokholyan

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Nikolay V Dokholyan

3

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author name string

Sagar D Khare

1

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Michael Caplow

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language of work or name

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publication date

19 October 2004

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Proceedings of the National Academy of Sciences of the United States of America

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101

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42

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15094-9

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Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture

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20 March 2017

ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

20 March 2017

Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

20 March 2017

Misfolded CuZnSOD and amyotrophic lateral sclerosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

20 March 2017

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

20 March 2017

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

20 March 2017

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

20 March 2017

Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

20 March 2017

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

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https://api.crossref.org/works/10.1073/PNAS.0406650101

22 April 2017

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

7 April 2017

Amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

7 April 2017

Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis show enhanced formation of aggregates in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

29 September 2017

Common denominator of Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis: decreased stability of the apo state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

29 September 2017

Amyotrophic lateral sclerosis: a proposed mechanism

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

29 September 2017

Dissociation of the tubulin dimer is extremely slow, thermodynamically very unfavorable, and reversible in the absence of an energy source

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

29 September 2017

Superoxide dismutase and the death of motoneurons in ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

29 September 2017

Current status of SOD1 mutations in familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

29 September 2017

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

29 September 2017

A glimpse of a possible amyloidogenic intermediate of transthyretin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

29 September 2017

Kinetic theory of fibrillogenesis of amyloid beta-protein

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

29 September 2017

Molecular genetic basis of familial ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

29 September 2017

Instability of mutant Cu/Zn superoxide dismutase (Ala4Thr) associated with familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

29 September 2017

Subunit association and side-chain reactivities of bovine erythrocyte superoxide dismutase in denaturing solvents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

29 September 2017

Loss of in vitro metal ion binding specificity in mutant copper-zinc superoxide dismutases associated with familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

2 June 2018

Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

2 June 2018

On the stability of bovine superoxide dismutase. The effects of metals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

2 June 2018

Contribution of conformational stability and reversibility of unfolding to the increased thermostability of human and bovine superoxide dismutase mutated at free cysteines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

2 June 2018

Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406650101

21 January 2018

Oxidation-induced misfolding and aggregation of superoxide dismutase and its implications for amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406650101

21 January 2018

High molecular weight complexes of mutant superoxide dismutase 1: age-dependent and tissue-specific accumulation

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406650101

21 January 2018

Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406650101

21 January 2018

Folding of Cu, Zn superoxide dismutase and familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406650101

21 January 2018

Familial amyotrophic lateral sclerosis-associated mutations decrease the thermal stability of distinctly metallated species of human copper/zinc superoxide dismutase

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406650101

21 January 2018

Structural properties of an amyloid precursor of beta(2)-microglobulin

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406650101

21 January 2018

Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406650101

21 January 2018

An intersubunit disulfide bond prevents in vitro aggregation of a superoxide dismutase-1 mutant linked to familial amytrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406650101

21 January 2018

Is polyproline II helix the killer conformation? a raman optical activity study of the amyloidogenic prefibrillar intermediate of human lysozyme 1 1Edited by A. R. Fersht

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406650101

21 January 2018

Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=524068

27 November 2018

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural analyses of various Cu2+, Zn2+-superoxide dismutases by differential scanning calorimetry and Raman spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociation of dimer of bovine erythrocyte Cu,Zn-superoxide dismutase and activity of the monomer subunit: effects of urea, temperature, and enzyme concentration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cu/Zn superoxide dismutase-like immunoreactivity in Lewy body-like inclusions of sporadic amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sporadic amyotrophic lateral sclerosis with dementia and Cu/Zn superoxide dismutase-positive Lewy body-like inclusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical study on superoxide dismutases in spinal cords from autopsied patients with amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pH-dependent stability and conformation of the recombinant human prion protein PrP(90-231)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the tertiary and quaternary structures in the stability of dimeric copper, zinc superoxide dismutases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0406650101

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2004PNAS..10115094K

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release_gyzgvrefwfh3za5kpjzak54na4

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https://api.fatcat.wiki/v0/release/gyzgvrefwfh3za5kpjzak54na4

24 November 2022

based on heuristic

mapped directly with Wikidata item

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