Troponin T core structure and the regulatory NH2-terminal variable region (Q28285624)

1

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Stephen M Chong

2

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Thomas M Nosek

3

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Jian-Ping Jin

Selective deletion of the NH2-terminal variable region of cardiac troponin T in ischemia reperfusion by myofibril-associated mu-calpain cleavage

4

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language of work or name

English

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publication date

6 February 2007

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published in

Biochemistry

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volume

46

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issue

5

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page(s)

1368-79

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cites work

1 reference

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Ca(2+)-regulated structural changes in troponin

20 March 2017

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Cellular fate of truncated slow skeletal muscle troponin T produced by Glu180 nonsense mutation in amish nemaline myopathy

20 March 2017

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Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form

20 March 2017

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Truncation by Glu180 nonsense mutation results in complete loss of slow skeletal muscle troponin T in a lethal nemaline myopathy

20 March 2017

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Cardiac troponin T isoforms affect the Ca2+ sensitivity and inhibition of force development. Insights into the role of troponin T isoforms in the heart

20 March 2017

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Functional consequences of caspase activation in cardiac myocytes

20 March 2017

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The highly conserved COOH terminus of troponin I forms a Ca2+-modulated allosteric domain in the troponin complex

20 March 2017

1 reference

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A proteolytic NH2-terminal truncation of cardiac troponin I that is up-regulated in simulated microgravity

20 March 2017

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Close physical linkage of human troponin genes: organization, sequence, and expression of the locus encoding cardiac troponin I and slow skeletal troponin T

20 March 2017

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Genomic sequence and structural organization of mouse slow skeletal muscle troponin T gene

20 March 2017

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Troponin T: genetics, properties and function

20 March 2017

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Three alternatively spliced mouse slow skeletal muscle troponin T isoforms: conserved primary structure and regulated expression during postnatal development

20 March 2017

1 reference

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Expression of cDNAs encoding mouse cardiac troponin T isoforms: characterization of a large sample of independent clones

20 March 2017

1 reference

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The effects of troponin T fragments T1 and T2 on the binding of nonpolymerizable tropomyosin to F-actin in the presence and absence of troponin I and troponin C

20 March 2017

1 reference

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Isolation and characterization of cDNA clones encoding embryonic and adult isoforms of rat cardiac troponin T

20 March 2017

1 reference

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Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle

20 March 2017

1 reference

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Deletion of the first 45 NH2-terminal residues of rabbit skeletal troponin T strengthens binding of troponin to immobilized tropomyosin

20 March 2017

1 reference

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Complete nucleotide sequence and structural organization of rat cardiac troponin T gene. A single gene generates embryonic and adult isoforms via developmentally regulated alternative splicing

20 March 2017

1 reference

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Regulation of contraction in striated muscle

20 March 2017

1 reference

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Exon skipping in cardiac troponin T of turkeys with inherited dilated cardiomyopathy

20 March 2017

1 reference

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Evolution of a metal-binding cluster in the NH(2)-terminal variable region of avian fast skeletal muscle troponin T: functional divergence on the basis of tolerance to structural drifting

29 September 2017

1 reference

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Acidic and basic troponin T isoforms in mature fast-twitch skeletal muscle and effect on contractility

29 September 2017

1 reference

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The N-terminal region of troponin T is essential for the maximal activation of rat cardiac myofilaments

29 September 2017

1 reference

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Developmentally regulated, alternative RNA splicing-generated pectoral muscle-specific troponin T isoforms and role of the NH2-terminal hypervariable region in the tolerance to acidosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Conformational modulation of troponin T by configuration of the NH2-terminal variable region and functional effects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Molecular polarity in tropomyosin-troponin T co-crystals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Primary structure and developmental acidic to basic transition of 13 alternatively spliced mouse fast skeletal muscle troponin T isoforms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Thin filament-mediated regulation of cardiac contraction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Cloned rat cardiac titin class I and class II motifs. Expression, purification, characterization, and interaction with F-actin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

An embryonic alternative transcription initiation site and the 5'-upstream structure of mouse cardiac troponin T gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Thin filament proteins and thin filament-linked regulation of vertebrate muscle contraction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Complete nucleotide sequence of the fast skeletal troponin T gene. Alternatively spliced exons exhibit unusual interspecies divergence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Sequences of complete cDNAs encoding four variants of chicken skeletal muscle troponin T.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Complete nucleotide sequence and structural organization of rat cardiac troponin T gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Conformational modulation of slow skeletal muscle troponin T by an NH(2)-terminal metal-binding extension.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Two-site attachment of troponin to pyrene-labeled tropomyosin

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Expression in Escherichia coli and a functional study of a beta-troponin T 25 kDa fragment of rabbit skeletal muscle

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Cardiac troponin T variants produced by aberrant splicing of multiple exons in animals with high instances of dilated cardiomyopathy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Fast skeletal muscle troponin T increases the cooperativity of transgenic mouse cardiac muscle contraction.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Structure of the Lethocerus troponin-tropomyosin complex as determined by electron microscopy.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794682

Structural interpretation of the two-site binding of troponin on the muscle thin filament

27 November 2018

1 reference

12 December 2020

Binding of troponin-T fragments to several types of tropomyosin. Sensitivity to Ca2+ in the presence of troponin-C

1 reference

12 December 2020

21 Preparation and identification of α- and β-tropomyosins

1 reference

12 December 2020

Modulation of troponin T molecular conformation and flexibility by metal ion binding to the NH2-terminal variable region

1 reference

12 December 2020

A 26K fragment of troponin T from rabbit skeletal muscle

1 reference

12 December 2020

Monoclonal antibodies against chicken tropomyosin isoforms: production, characterization, and application

1 reference

12 December 2020

Isolation and functional comparison of bovine cardiac troponin T isoforms

1 reference

12 December 2020

Effect of phosphorylation on the interaction and functional properties of rabbit striated muscle alpha alpha-tropomyosin

1 reference

12 December 2020

Interaction of rabbit skeletal muscle troponin T and F-actin at physiological ionic strength

1 reference

12 December 2020

Transgenic analysis of the thyroid-responsive elements in the alpha-cardiac myosin heavy chain gene promoter

1 reference

12 December 2020

NH2-terminal truncation of skeletal muscle troponin T does not alter the Ca2+ sensitivity of thin filament assembly

1 reference

12 December 2020

Separation and characterization of the two functional regions of troponin involved in muscle thin filament regulation

1 reference

12 December 2020

Molecular Arrangement of Troponin-T in the Thin Filament1

1 reference

12 December 2020

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