Molecular screening of the human glutamine-fructose-6-phosphate amidotransferase 1 (GFPT1) gene and association studies with diabetes and diabetic nephropathy (Q28276860)

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English	Molecular screening of the human glutamine-fructose-6-phosphate amidotransferase 1 (GFPT1) gene and association studies with diabetes and diabetic nephropathy	scientific article

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Molecular screening of the human glutamine-fructose-6-phosphate amidotransferase 1 (GFPT1) gene and association studies with diabetes and diabetic nephropathy (English)

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diabetic nephropathy

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based on heuristic

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author name string

Steven C Elbein

1

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Hailing Zheng

2

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Yiwen Jia

3

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Winston Chu

4

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Judith J Cooper

5

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Terri Hale

6

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Zhengxian Zhang

7

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language of work or name

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publication date

August 2004

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Molecular Genetics and Metabolism

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82

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4

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321-8

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Biochemistry and molecular cell biology of diabetic complications

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Hexosamines as mediators of nutrient sensing and regulation in diabetes.

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Perspective: Hexosamines and nutrient sensing

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Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

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Effects of overexpression of glutamine:fructose-6-phosphate amidotransferase (GFAT) and glucosamine treatment on translocation of GLUT4 in rat adipose cells

1 reference

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High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells

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Transcriptional regulation of transforming growth factor beta1 by glucose: investigation into the role of the hexosamine biosynthesis pathway

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Transgenic mice overexpressing the rate-limiting enzyme for hexosamine synthesis in skeletal muscle or adipose tissue exhibit total body insulin resistance.

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Overexpression of glutamine:fructose-6-phosphate amidotransferase in transgenic mice leads to insulin resistance

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Transgenic mice with increased hexosamine flux specifically targeted to beta-cells exhibit hyperinsulinemia and peripheral insulin resistance.

1 reference

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A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians

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Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms

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Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern European Caucasians

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Molecular scanning analysis of hepatocyte nuclear factor 1alpha (TCF1) gene in typical familial type 2 diabetes in African Americans

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Mutation screening using automated bidirectional dideoxy fingerprinting

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Pyrosequencing: an accurate detection platform for single nucleotide polymorphisms

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Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans

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Optimal step length EM algorithm (OSLEM) for the estimation of haplotype frequency and its application in lipoprotein lipase genotyping

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Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium

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Natural variation in human gene expression assessed in lymphoblastoid cells

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10.1016/J.YMGME.2004.05.004

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