A designed point mutant in Fis1 disrupts dimerization and mitochondrial fission (Q28270916)

2

0 references

Lora K Picton

3

0 references

Alexandra Z Ebie Tan

4

0 references

Salvador Casares

5

0 references

John M Flanagan

6

0 references

Karen G Fleming

7

0 references

R Blake Hill

Journal of Molecular Biology

8

0 references

language of work or name

English

0 references

publication date

19 October 2012

0 references

published in

0 references

volume

423

0 references

page(s)

143-58

0 references

issue

2

0 references

describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3456991/fullTextXML

inferred from PubMed Central ID database lookup

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The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells

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Fis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesis

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Crystal structure of murine CstF-77: dimeric association and implications for polyadenylation of mRNA precursors

20 March 2017

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Failure of microtubule-mediated peroxisome division and trafficking in disorders with reduced peroxisome abundance

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Regulation of mitochondrial fission and apoptosis by the mitochondrial outer membrane protein hFis1

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A role for Fis1 in both mitochondrial and peroxisomal fission in mammalian cells

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The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria

20 March 2017

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Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission.

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Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers

20 March 2017

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Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology

20 March 2017

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The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle

20 March 2017

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The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1

20 March 2017

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hFis1, a novel component of the mammalian mitochondrial fission machinery

20 March 2017

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The dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11

20 March 2017

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Dynamin-like protein 1 is involved in peroxisomal fission

20 March 2017

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Two structures of cyclophilin 40: folding and fidelity in the TPR domains

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An unexpected extended conformation for the third TPR motif of the peroxin PEX5 from Trypanosoma brucei

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Role of rapsyn tetratricopeptide repeat and coiled-coil domains in self-association and nicotinic acetylcholine receptor clustering

20 March 2017

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Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p

20 March 2017

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Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division

20 March 2017

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Gag3p, an outer membrane protein required for fission of mitochondrial tubules

20 March 2017

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A human dynamin-related protein controls the distribution of mitochondria

20 March 2017

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20 March 2017

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Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae

20 March 2017

1 reference

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Structural basis of calcium-induced E-cadherin rigidification and dimerization

20 March 2017

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3D domain swapping: a mechanism for oligomer assembly

20 March 2017

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20 March 2017

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A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy

20 March 2017

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Analysis of functional domains of rat mitochondrial Fis1, the mitochondrial fission-stimulating protein

20 March 2017

1 reference

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pH-dependent tetramerization and amantadine binding of the transmembrane helix of M2 from the influenza A virus

20 March 2017

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The cytosolic domain of Fis1 binds and reversibly clusters lipid vesicles

20 March 2017

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Versatile TPR domains accommodate different modes of target protein recognition and function

29 September 2017

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A lethal de novo mutation in the middle domain of the dynamin-related GTPase Drp1 impairs higher order assembly and mitochondrial division

29 September 2017

1 reference

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Evidence for conformational heterogeneity of fission protein Fis1 from Saccharomyces cerevisiae

29 September 2017

1 reference

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Crystal structure of the N-terminal domain of anaphase-promoting complex subunit 7.

29 September 2017

1 reference

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Organelle dynamics and dysfunction: A closer link between peroxisomes and mitochondria

29 September 2017

1 reference

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Protein metamorphosis: the two-state behavior of Mad2.

29 September 2017

1 reference

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Mitochondrial fusion and function in Charcot-Marie-Tooth type 2A patient fibroblasts with mitofusin 2 mutations

29 September 2017

1 reference

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Direct binding of the dynamin-like GTPase, Dnm1, to mitochondrial dynamics protein Fis1 is negatively regulated by the Fis1 N-terminal arm

29 September 2017

1 reference

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Get the balance right: mitofusins roles in health and disease

29 September 2017

1 reference

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Energetics of outer membrane phospholipase A (OMPLA) dimerization.

29 September 2017

1 reference

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Dysregulation of mitochondrial fusion and fission: an emerging concept in neurodegeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

The role of Fis1p-Mdv1p interactions in mitochondrial fission complex assembly

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

The unfolding story of three-dimensional domain swapping.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fission

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

Active monomeric and dimeric forms of Pseudomonas putida glyoxalase I: evidence for 3D domain swapping.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

Sgt1 dimerization is required for yeast kinetochore assembly

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

A lethal defect of mitochondrial and peroxisomal fission

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

Mitochondrial dynamics in disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

Explaining the oligomerization properties of the spindle assembly checkpoint protein Mad2.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

Insights into the conformational dynamics of the E3 ubiquitin ligase CHIP in complex with chaperones and E2 enzymes.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

Biochemistry. Metamorphic proteins.

27 November 2018

1 reference

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Heat-Induced Dimerization of BCL-xLthrough α-Helix Swapping†

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

Fis1p and Caf4p, but not Mdv1p, determine the polar localization of Dnm1p clusters on the mitochondrial surface.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

BCL-XL dimerization by three-dimensional domain swapping.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

Intra- and intermolecular domain interactions of the C-terminal GTPase effector domain of the multimeric dynamin-like GTPase Drp1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

Spatial and temporal dynamics of budding yeast mitochondria lacking the division component Fis1p

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

Observation of signal transduction in three-dimensional domain swapping

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

The effect of point mutations on the free energy of transmembrane alpha-helix dimerization.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

A thermodynamic scale for the helix-forming tendencies of the commonly occurring amino acids

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3456991

When one and one are not two

27 November 2018

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12 December 2020

Mitochondrial dynamics in yeast

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12 December 2020

The crystal structure of the secreted dimeric form of the hemophore HasA reveals a domain swapping with an exchanged heme ligand

1 reference

12 December 2020

TPR-Mediated self-association of plant SGT1

1 reference

12 December 2020

EQUILIBRIUM ULTRACENTRIFUGATION OF DILUTE SOLUTIONS

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12 December 2020