Mechanisms and functions of DNA mismatch repair (Q28262719)

Eukaryotic DNA mismatch repair

Europe PubMed Central

title

Mechanisms and functions of DNA mismatch repair (English)

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Guo-Min Li

1

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language of work or name

English

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publication date

January 2008

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published in

Cell Research

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volume

18

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page(s)

85-98

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issue

1

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cites work

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20 April 2017

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Structure and function of mismatch repair proteins

20 April 2017

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Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA

20 April 2017

1 reference

The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch

20 April 2017

1 reference

Partial reconstitution of human DNA mismatch repair in vitro: characterization of the role of human replication protein A

20 April 2017

1 reference

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

20 April 2017

1 reference

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

20 April 2017

1 reference

GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells

20 April 2017

1 reference

Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells

20 April 2017

1 reference

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

20 April 2017

1 reference

Mutation of a mutL homolog in hereditary colon cancer

20 April 2017

1 reference

Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2

20 April 2017

1 reference

The evolutionarily conserved zinc finger motif in the largest subunit of human replication protein A is required for DNA replication and mismatch repair but not for nucleotide excision repair

20 April 2017

1 reference

ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair

20 April 2017

1 reference

Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair

20 April 2017

1 reference

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

20 April 2017

1 reference

DNA polymerase delta is required for human mismatch repair in vitro

20 April 2017

1 reference

MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability

20 April 2017

1 reference

MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp

20 April 2017

1 reference

Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes

20 April 2017

1 reference

Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex

20 April 2017

1 reference

hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci

20 April 2017

1 reference

exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair

20 April 2017

1 reference

Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA

20 April 2017

1 reference

Mechanism of 5'-directed excision in human mismatch repair

20 April 2017

1 reference

A defined human system that supports bidirectional mismatch-provoked excision

20 April 2017

1 reference

Human exonuclease I is required for 5' and 3' mismatch repair

20 April 2017

1 reference

Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility

20 April 2017

1 reference

Evidence for involvement of HMGB1 protein in human DNA mismatch repair

20 April 2017

1 reference

The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch

20 April 2017

1 reference

DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair

20 April 2017

1 reference

Mismatch repair deficiency associated with overexpression of the MSH3 gene

20 April 2017

1 reference

The mismatch repair system is required for S-phase checkpoint activation

20 April 2017

1 reference

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

20 April 2017

1 reference

Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin

20 April 2017

1 reference

ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts

20 April 2017

1 reference

Cancer genes and the pathways they control

20 April 2017

1 reference

SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination

20 April 2017

1 reference

RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination

20 April 2017

1 reference

The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells

20 April 2017

1 reference

Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice

20 April 2017

1 reference

Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2

20 April 2017

1 reference

Trinucleotide repeats that expand in human disease form hairpin structures in vitro

20 April 2017

1 reference

Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice

20 April 2017

1 reference

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

20 April 2017

1 reference

Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair

20 April 2017

1 reference

Mouse models for human DNA mismatch-repair gene defects

20 April 2017

1 reference

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

20 April 2017

1 reference

MSH2 deficient mice are viable and susceptible to lymphoid tumours

20 April 2017

1 reference

Mutation in the mismatch repair gene Msh6 causes cancer susceptibility

20 April 2017

1 reference

HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions

20 April 2017

1 reference

Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

20 April 2017

1 reference

Meiotic pachytene arrest in MLH1-deficient mice

20 April 2017

1 reference

Meiotic arrest and aneuploidy in MLH3-deficient mice

20 April 2017

1 reference

Cancer-susceptibility genes. Gatekeepers and caretakers

20 April 2017

1 reference

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

20 April 2017

1 reference

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Marker discrimination in transformation and mutation of pneumococcus

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Mismatch repair and DNA damage signalling

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Mammalian DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

The multifaceted mismatch-repair system

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

DNA mismatch repair: molecular mechanisms and biological function

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

DNA mismatch correction in a defined system

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Endonucleolytic function of MutLalpha in human mismatch repair.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Molecular matchmakers

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesis

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Dominant negative mutator mutations in the mutL gene of Escherichia coli

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Escherichia coli mismatch repair protein MutL interacts with the clamp loader subunits of DNA polymerase III.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

The beta sliding clamp binds to multiple sites within MutL and MutS.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Reconstitution of 5'-directed human mismatch repair in a purified system

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Transfer of the MSH2.MSH6 complex from proliferating cell nuclear antigen to mispaired bases in DNA.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Differential requirement for proliferating cell nuclear antigen in 5' and 3' nick-directed excision in human mismatch repair

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

EXO1-A multi-tasking eukaryotic nuclease.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Regulation of replication protein A functions in DNA mismatch repair by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

The high mobility group domain protein Cmb1 of Schizosaccharomyces pombe binds to cytosines in base mismatches and opposite chemically altered guanines.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Nonhistone Proteins HMG 1 and HMG 2 Change the DNA Helical Structure

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Nonhistone proteins HMG1and HMG2unwind DNA double helix

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Signaling from DNA mispairs to mismatch-repair excision sites despite intervening blockades

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

MutS mediates heteroduplex loop formation by a translocation mechanism

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Mismatch repair, molecular switches, and signal transduction.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Detection of high-affinity and sliding clamp modes for MSH2-MSH6 by single-molecule unzipping force analysis

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Analysis of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 complexes with DNA using a reversible DNA end-blocking system.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Dual bidirectional promoters at the mouse dhfr locus: cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

MLH1- and ATM-dependent MAPK signaling is activated through c-Abl in response to the alkylator N-methyl-N'-nitro-N'-nitrosoguanidine

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Mismatch repair-dependent iterative excision at irreparable O6-methylguanine lesions in human nuclear extracts

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Maintenance of genome stability in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

DNA mismatch repair and genetic instability

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Distinct roles for the Saccharomyces cerevisiae mismatch repair proteins in heteroduplex rejection, mismatch repair and nonhomologous tail removal

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

The Bloom's syndrome helicase interacts directly with the human DNA mismatch repair protein hMSH6.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Double-strand breaks induce homologous recombinational repair of interstrand cross-links via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

hMutSbeta is required for the recognition and uncoupling of psoralen interstrand cross-links in vitro

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Involvement of DNA mismatch repair in folate deficiency-induced apoptosis☆

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

DNA repair in antibody somatic hypermutation

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Repeat instability: mechanisms of dynamic mutations

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

(CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Clues to the pathogenesis of familial colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Microsatellite instability in cancer of the proximal colon

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

DNA mismatch repair and cancer

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Mismatch repair deficiency in hematological malignancies with microsatellite instability

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Deficiency of a novel mismatch repair activity in a bladder tumor cell line

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Genetic and epigenetic alterations in colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Inheritance of a Cancer-AssociatedMLH1Germ-Line Epimutation

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Germline epimutation of MLH1 in individuals with multiple cancers.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.115

7 January 2021