Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis (Q28261784)

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29 December 2019

title

Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis (English)

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Elvira Crescenzi

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Morag C Martin

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Hugh Brady

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Ian Dransfield

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29 December 2019

author name string

Adriano G Rossi

1

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Deborah A Sawatzky

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Annemieke Walker

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Carol Ward

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Tara A Sheldrake

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Nicola A Riley

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Alison Caldicott

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Magdalena Martinez-Losa

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Trevor R Walker

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Mohini Gray

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John S Savill

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Christopher Haslett

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language of work or name

English

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publication date

3 September 2006

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29 December 2019

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29 December 2019

volume

12

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29 December 2019

page(s)

1056-1064

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29 December 2019

issue

9

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Points of control in inflammation

29 December 2019

cites work

1 reference

7 January 2021

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages

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7 January 2021

Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

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Inflammatory resolution: new opportunities for drug discovery

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Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis.

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The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer

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Small-molecule cyclin-dependent kinase modulators

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Cyclin-dependent kinase inhibitors: cancer killers to neuronal guardians

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7 January 2021

Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1

1 reference

7 January 2021

Seliciclib (CYC202 or R-roscovitine), a small-molecule cyclin-dependent kinase inhibitor, mediates activity via down-regulation of Mcl-1 in multiple myeloma

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7 January 2021

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7 January 2021

Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine

1 reference

7 January 2021

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

1 reference

7 January 2021

Roscovitine targets, protein kinases and pyridoxal kinase

1 reference

7 January 2021

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

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7 January 2021

Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors

1 reference

7 January 2021

Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent

1 reference

7 January 2021

Activation of Cdk2 is a requirement for antigen-mediated thymic negative selection

1 reference

7 January 2021

Cyclic AMP regulation of neutrophil apoptosis occurs via a novel protein kinase A-independent signaling pathway.

1 reference

7 January 2021

NF-κB Activation Is a Critical Regulator of Human Granulocyte Apoptosisin Vitro

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7 January 2021

Interleukin-10 inhibits lipopolysaccharide-induced survival and extracellular signal-regulated kinase activation in human neutrophils.

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7 January 2021

Toll-like receptor (TLR)2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses

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7 January 2021

Selective roles for Toll-like receptor (TLR)2 and TLR4 in the regulation of neutrophil activation and life span.

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7 January 2021

GTP-dependent secretion from neutrophils is regulated by Cdk5.

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7 January 2021

Inducible cyclooxygenase may have anti-inflammatory properties

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7 January 2021

Inducible cyclooxygenase-derived 15-deoxyΔ12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis

1 reference

7 January 2021

The involvement of the apoptosis-modulating proteins ERK 1/2, Bcl-xL and Bax in the resolution of acute inflammation in vivo

1 reference

7 January 2021

Resident pleural macrophages are key orchestrators of neutrophil recruitment in pleural inflammation

1 reference

7 January 2021

End-stage differentiation of neutrophil granulocytes in vivo is accompanied by up-regulation of p27kip1 and down-regulation of CDK2, CDK4, and CDK6

1 reference

7 January 2021

Gene expression in human neutrophils during activation and priming by bacterial lipopolysaccharide.

1 reference

7 January 2021

Gene expression in mature neutrophils: early responses to inflammatory stimuli

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7 January 2021

RNA expression patterns change dramatically in human neutrophils exposed to bacteria

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7 January 2021

Spontaneous neutrophil apoptosis and regulation of cell survival by granulocyte macrophage-colony stimulating factor

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7 January 2021

Bleomycin lung toxicity: who are the patients with increased risk?

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7 January 2021

A pivotal role of cytosolic phospholipase A(2) in bleomycin-induced pulmonary fibrosis

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7 January 2021

Resolution of lung inflammation by CD44

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7 January 2021

Fas/FasL-mediated apoptosis in perinatal murine lungs

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7 January 2021

Lipid mediator class switching during acute inflammation: signals in resolution.

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7 January 2021

Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals

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7 January 2021

Resolution of inflammation: the beginning programs the end

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7 January 2021

Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes.

1 reference

7 January 2021

Phosphoinositide-3 kinases critically regulate the recruitment and survival of eosinophils in vivo: importance for the resolution of allergic inflammation

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7 January 2021

In vitro and in vivo antitumor properties of the cyclin dependent kinase inhibitor CYC202 (R-roscovitine)

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7 January 2021

Inflammation and cancer

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7 January 2021

NF-kappaB: linking inflammation and immunity to cancer development and progression

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7 January 2021

A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis.

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM1468

2 references

Consolidated OpenCitations Corpus – April 2017

1072287

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29 December 2019

1072287

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

1072287

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