Neurexins: three genes and 1001 products (Q28260363)

Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin

Europe PubMed Central

title

Neurexins: three genes and 1001 products (English)

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author

Thomas C. Südhof

series ordinal

2

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Markus Missler

object named as

M Missler

series ordinal

1

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language of work or name

English

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publication date

January 1998

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published in

Trends in Genetics

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volume

14

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page(s)

20-6

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issue

1

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cites work

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7 January 2021

Cartography of neurexins: more than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons.

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7 January 2021

Structural study of long arm fragments of laminin. Evidence for repetitive C-terminal sequences in the A-chain, not present in the B-chains

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A Drosophila neurexin is required for septate junction and blood-nerve barrier formation and function.

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Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions

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The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycans

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A synthetic peptide derived from the carboxy terminus of the laminin A chain represents a binding site for the alpha 3 beta 1 integrin

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Neuroligin 1: a splice site-specific ligand for beta-neurexins

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Structures, alternative splicing, and neurexin binding of multiple neuroligins

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Alpha-latrotoxin and related toxins

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Distinct Ca2+ and Sr2+ binding properties of synaptotagmins. Definition of candidate Ca2+ sensors for the fast and slow components of neurotransmitter release

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Isolation and biochemical characterization of a Ca2+-independent alpha-latrotoxin-binding protein.

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The calcium-independent receptor of alpha-latrotoxin is not a neurexin.

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Structure and evolution of neurexophilin

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Gliotactin, a novel transmembrane protein on peripheral glia, is required to form the blood-nerve barrier in Drosophila.

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Binding properties of neuroligin 1 and neurexin 1beta reveal function as heterophilic cell adhesion molecules

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Tight junctions, membrane-associated guanylate kinases and cell signaling

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PDZs and receptor/channel clustering: rounding up the latest suspects

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CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins

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Binding of neuroligins to PSD-95

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PSD-95 is associated with the postsynaptic density and not with the presynaptic membrane at forebrain synapses

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Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ

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The primary structure of NG2, a novel membrane-spanning proteoglycan

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Molecular cloning and tissue expression of FAT, the human homologue of the Drosophila fat gene that is located on chromosome 4q34-q35 and encodes a putative adhesion molecule

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A Drosophila homolog of cadherin associated with armadillo and essential for embryonic cell-cell adhesion.

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crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia.

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Molecular cloning of a novel laminin chain, alpha 5, and widespread expression in adult mouse tissues.

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The complete cDNA sequence of laminin alpha 4 and its relationship to the other human laminin alpha chains

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slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains

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The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade

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7 January 2021

Neurexin is expressed on nerves, but not at nerve terminals, in the electric organ.

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7 January 2021