Tau imaging: early progress and future directions (Q28253740)

Frequency of stages of Alzheimer-related lesions in different age categories

Europe PubMed Central

title

Tau imaging: early progress and future directions (English)

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3

Colin L Masters

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author name string

Victor L Villemagne

series ordinal

1

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Michelle T Fodero-Tavoletti

series ordinal

2

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Christopher C Rowe

series ordinal

4

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language of work or name

English

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publication date

January 2015

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published in

Lancet Neurology

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volume

14

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page(s)

114-24

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issue

1

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

18F-THK523: a novel in vivo tau imaging ligand for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Rates of β-amyloid accumulation are independent of hippocampal neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Imaging beta-amyloid burden in aging and dementia.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Neuropathological alterations in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

One hundred years after the discovery of Alzheimer's disease. A turning point for therapy?

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Challenges in the conduct of disease-modifying trials in AD: practical experience from a phase 2 trial of Tau-aggregation inhibitor therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

TAR DNA-binding protein 43 in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Neurodegenerative tauopathies

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

The ART of loss: Abeta imaging in the evaluation of Alzheimer's disease and other dementias

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Linking amyloid-β and tau: amyloid-β induced synaptic dysfunction via local wreckage of the neuronal cytoskeleton.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

1 reference

7 January 2021

Ultrastructural characteristics of tau filaments in tauopathies: immuno-electron microscopic demonstration of tau filaments in tauopathies.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Evolution of neuronal changes in the course of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Transmission and spreading of tauopathy in transgenic mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

In vivo tau imaging: obstacles and progress.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Human Tau isoforms assemble into ribbon-like fibrils that display polymorphic structure and stability

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Biochemistry of Tau in Alzheimer's disease and related neurological disorders.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Post-translational modifications of tau protein: implications for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Tau aggregation is driven by a transition from random coil to beta sheet structure

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Triggers of full-length tau aggregation: a role for partially folded intermediates.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Characterization of tau fibrillization in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Tau protein pathology in neurodegenerative diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

PIB binding in aged primate brain: enrichment of high-affinity sites in humans with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Progressive supranuclear palsy and corticobasal degeneration: lumping versus splitting

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Levels of normal and abnormally phosphorylated tau in different cellular and regional compartments of Alzheimer disease and control brains.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

PET radiotracers: crossing the blood-brain barrier and surviving metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Quinoline and benzimidazole derivatives: candidate probes for in vivo imaging of tau pathology in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

A highly selective and specific PET tracer for imaging of tau pathologies

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Evaluation of [(11)C]N-Methyl Lansoprazole as a Radiopharmaceutical for PET Imaging of Tau Neurofibrillary Tangles.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Selectivity requirements for diagnostic imaging of neurofibrillary lesions in Alzheimer's disease: a simulation study.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

α-synuclein imaging: a critical need for Parkinson's disease research.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Binding of the radioligand SIL23 to α-synuclein fibrils in Parkinson disease brain tissue establishes feasibility and screening approaches for developing a Parkinson disease imaging agent

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

In vivo visualization of alpha-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy]benzoxazole positron emission tomography in multiple system atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Postmortem 3-D brain hemisphere cortical tau and amyloid-β pathology mapping and quantification as a validation method of neuropathology imaging.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

PET of brain amyloid and tau in mild cognitive impairment.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Positron emission tomography of brain β-amyloid and τ levels in adults with Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

PET Scanning of Brain Tau in Retired National Football League Players: Preliminary Findings

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

PET imaging of neuropathology in tauopathies: progressive supranuclear palsy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Molecular-imaging probe 2-(1-[6-[(2-fluoroethyl)(methyl) amino]-2-naphthyl]ethylidene) malononitrile labels prion plaques in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

PET of brain prion protein amyloid in Gerstmann-Sträussler-Scheinker disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Detection of Alzheimer pathology in vivo using both 11C-PIB and 18F-FDDNP PET.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Multitracer PET imaging of amyloid plaques and neurofibrillary tangles in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Amyloid imaging in aged and young macaques with [11C]PIB and [18F]FDDNP.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Interaction of the amyloid imaging tracer FDDNP with hallmark Alzheimer's disease pathologies

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Novel 18F-labeled arylquinoline derivatives for noninvasive imaging of tau pathology in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Comparison of the binding characteristics of [18F]THK-523 and other amyloid imaging tracers to Alzheimer's disease pathology

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Assessing THK523 selectivity for tau deposits in Alzheimer's disease and non-Alzheimer's disease tauopathies.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

In vivo evaluation of a novel tau imaging tracer for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

[(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

High affinity radiopharmaceuticals based upon lansoprazole for PET imaging of aggregated tau in Alzheimer's disease and progressive supranuclear palsy: synthesis, preclinical evaluation, and lead selection

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Radiosynthesis, photoisomerization, biodistribution, and metabolite analysis of 11C-PBB3 as a clinically useful PET probe for imaging of tau pathology.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Tauopathy PET and amyloid PET in the diagnosis of chronic traumatic encephalopathies: studies of a retired NFL player and of a man with FTD and a severe head injury.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Biomarker modeling of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Tau aggregation in the hippocampal formation: an ageing or a pathological process?

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Alzheimer disease: Aβ-independent processes-rethinking preclinical AD.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Is aging part of Alzheimer's disease, or is Alzheimer's disease part of aging?

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Location, location, location!

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

Observations on the brains of demented old people

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2814%2970252-2

7 January 2021

10.1016/S1474-4422(14)70252-2

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

415689

415689

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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