Anti-LRP4 autoantibodies in AChR- and MuSK-antibody-negative myasthenia gravis (Q28244847)

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ORCID Public Data File 2021

author name string

Alexandra Pevzner

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Katja Peters

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Nicoleta-Carmen Cosma

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Andromachi Karakatsani

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Arthur Melms

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Stephan Kröger

https://scigraph.springernature.com/pub.10.1007/s00415-011-6194-7

8

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language of work or name

English

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publication date

March 2012

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published in

Journal of Neurology

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volume

259

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page(s)

427-35

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issue

3

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exact match

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cites work

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The immunopathological basis of acetylcholine receptor deficiency in myasthenia gravis

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Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies

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Detection and characterization of MuSK antibodies in seronegative myasthenia gravis

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Anti-MuSK antibody myasthenia gravis: clinical findings and response to treatment in two large cohorts

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Receptor tyrosine kinase specific for the skeletal muscle lineage: expression in embryonic muscle, at the neuromuscular junction, and after injury

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Rapsyn is required for MuSK signaling and recruits synaptic components to a MuSK-containing scaffold

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Comparison of muscle ultrastructure in myasthenia gravis with anti-MuSK and anti-AChR antibodies.

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MuSK antibody positive myasthenia gravis plasma modifies MURF-1 expression in C2C12 cultures and mouse muscle in vivo

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Major pathogenic effects of anti-MuSK antibodies in myasthenia gravis

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Myasthenia gravis seronegative for acetylcholine receptor antibodies

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IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis

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Fewer thymic changes in MuSK antibody-positive than in MuSK antibody-negative MG.

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Seronegative myasthenia gravis: disease severity and prognosis

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Myasthenia gravis without acetylcholine-receptor antibody: a distinct disease entity

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LRP4 serves as a coreceptor of agrin

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Lrp4 is a receptor for Agrin and forms a complex with MuSK

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Autoantibodies to low-density lipoprotein receptor-related protein 4 in myasthenia gravis.

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Dystroglycan regulates structure, proliferation and differentiation of neuroepithelial cells in the developing vertebrate CNS.

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Agrin is a heparan sulfate proteoglycan

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Expression of mouse agrin in normal, denervated and dystrophic muscle

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Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active site

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Mutations in the gene encoding the low-density lipoprotein receptor LRP4 cause abnormal limb development in the mouse

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Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo

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Lrp4 regulates initiation of ureteric budding and is crucial for kidney formation--a mouse model for Cenani-Lenz syndrome

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Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice

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To build a synapse: signaling pathways in neuromuscular junction assembly

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The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo

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LRP4 mutations alter Wnt/beta-catenin signaling and cause limb and kidney malformations in Cenani-Lenz syndrome

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A myasthenia gravis plasma immunoglobulin reduces miniature endplate potentials at human endplates in vitro

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12 December 2020

Anti-p110 autoantibodies identify a subtype of "seronegative" myasthenia gravis with prominent oculobulbar involvement

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12 December 2020

The receptor tyrosine kinase MuSK is required for neuromuscular junction formation and is a functional receptor for agrin.

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12 December 2020

MuSK-antibody positive myasthenia gravis: questions from the clinic

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12 December 2020

The emerging diversity of neuromuscular junction disorders

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12 December 2020

Detection of multiple antibodies in myasthenia gravis and its clinical significance

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12 December 2020

Dimerization of the muscle-specific kinase induces tyrosine phosphorylation of acetylcholine receptors and their aggregation on the surface of myotubes

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12 December 2020

Myasthenia gravis: disease severity and prognosis

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12 December 2020

Antifilamin, antivinculin, and antitropomyosin antibodies in myasthenia gravis

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12 December 2020

Effect of sera from AChR-antibody negative myasthenia gravis patients on AChR and MuSK in cell cultures

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12 December 2020

Inhibition of agrin-induced acetylcholine-receptor aggregation by heparin, heparan sulfate, and other polyanions

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12 December 2020

Antibody-secreting cells to acetylcholine receptor and to presynaptic membrane receptor in seronegative myasthenia gravis

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12 December 2020