Current investigational drugs for major depression (Q28244223)

Expert Opinion on Investigational Drugs

Europe PubMed Central

title

Current investigational drugs for major depression (English)

0 references

2

Ashish Dhir

0 references

author name string

Shrinivas K Kulkarni

series ordinal

1

0 references

language of work or name

English

0 references

publication date

June 2009

0 references

published in

0 references

volume

18

0 references

page(s)

767-88

0 references

issue

6

0 references

cites work

Therapeutic applications of selective and non-selective inhibitors of monoamine oxidase A and B that do not cause significant tyramine potentiation

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

Is the forced swimming test a suitable model for revealing antidepressant activity?

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

Triple uptake inhibitors: therapeutic potential in depression and beyond

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

DOV 216,303, a "triple" reuptake inhibitor: safety, tolerability, and pharmacokinetic profile

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

Antidepressant-like actions of DOV 21,947: a "triple" reuptake inhibitor

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

Randomized trial of the triple monoamine reuptake inhibitor NS 2330 (tesofensine) in early Parkinson's disease

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

Antidepressant-like pharmacological profile of a novel triple reuptake inhibitor, (1S,2S)-3-(methylamino)-2-(naphthalen-2-yl)-1-phenylpropan-1-ol (PRC200-SS)

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

In-vitro and in-vivo characterization of JNJ-7925476, a novel triple monoamine uptake inhibitor

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

Regulating ankyrin dynamics: Roles of sigma-1 receptors

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

Dual- and triple-acting agents for treating core and co-morbid symptoms of major depression: novel concepts, new drugs

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

The novel cellular mechanism of human 5-HT6 receptor through an interaction with Fyn

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders.

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

Selective blockade of NK2 or NK3 receptors produces anxiolytic- and antidepressant-like effects in gerbils

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543780902880850

The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R)

21 April 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Pharmacology and functions of metabotropic glutamate receptors

21 April 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Research and treatment approaches to depression

21 April 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

From monoamines to genomic targets: a paradigm shift for drug discovery in depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Acceleration of the effect of selected antidepressant drugs in major depression by 5-HT1A antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Suicide and mental disorders in Asia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

The role of monoamines in the actions of established and "novel" antidepressant agents: a critical review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Advances in the treatment of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Definition and epidemiology of treatment-resistant depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

How many well vs. unwell days can you expect over 10 years, once you become depressed?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Pharmacological principles of antidepressant efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Role of the serotonergic system in the forced swimming test

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Psychopharmacological profile of the selective serotonin reuptake inhibitor, paroxetine: implication of noradrenergic and serotonergic mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Antidepressant and anxiolytic effects of alprazolam versus the conventional antidepressant desipramine and the anxiolytic diazepam in the forced swim test in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Behavioural despair in rats: A new model sensitive to antidepressant treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Intra- and interstrain differences in models of "behavioral despair".

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Antidepressant-like effects in various mice strains in the forced swimming test.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Monoamine metabolism changes following the mouse forced swimming test but not the tail suspension test.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Selective D-1 dopamine receptor increase following chronic treatment with SCH 23390.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Dopaminergic abnormalities in amygdaloid nuclei in major depression: a postmortem study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Fostering foster care outcomes: quality of intervention matters in overcoming early adversity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Lesions of dopaminergic neurons in the substantia nigra pars compacta and in the ventral tegmental area enhance depressive-like behavior in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of bupropion, a dopamine reuptake inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Effects of the dopamine agonist pramipexole on depression, anhedonia and motor functioning in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Involvement of dopamine (DA)/serotonin (5-HT)/sigma (sigma) receptor modulation in mediating the antidepressant action of ropinirole hydrochloride, a D2/D3 dopamine receptor agonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Presynaptic dopamine release is enhanced by 5-HT3 receptor activation in medial prefrontal cortex of freely moving rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Perfusate serotonin increases extracellular dopamine in the nucleus accumbens as measured by in vivo microdialysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Induction of burst firing in ventral tegmental area dopaminergic neurons by activation of serotonin (5-HT)1A receptors: WAY 100,635-reversible actions of the highly selective ligands, flesinoxan and S 15535.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

A case of transient hallucination with ropinirole augmentation antidepressant in a patient with treatment-resistant depression: Is there differential effect of ropinirole dose on developing psychotic symptom?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

The antidepressive-like effect of oxcarbazepine: possible role of dopaminergic neurotransmission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Triple reuptake inhibitors ("broad spectrum" antidepressants).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

The triple monoaminergic reuptake inhibitor DOV 216,303 has antidepressant effects in the rat olfactory bulbectomy model and lacks sexual side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Preclinical and clinical pharmacology of DOV 216,303, a "triple" reuptake inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Pharmacological profile of the "triple" monoamine neurotransmitter uptake inhibitor, DOV 102,677.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of venlafaxine in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Antidepressant-like effect of 17beta-estradiol: involvement of dopaminergic, serotonergic, and (or) sigma-1 receptor systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant activity of berberine chloride

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

On the mechanism of antidepressant-like action of berberine chloride

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Involvement of nitric oxide-cGMP pathway in the antidepressant-like effects of adenosine in the forced swimming test

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Evidence for the involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of memantine in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Involvement of NMDA receptors and L-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of tramadol in the rat forced swimming test

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Reduction of cGMP and nitric oxide has antidepressant-like effects in the forced swimming test in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

High occupancy of sigma-1 receptors in the human brain after single oral administration of fluvoxamine: a positron emission tomography study using [11C]SA4503.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

An update on the development of drugs for neuropsychiatric disorders: focusing on the sigma 1 receptor ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Involvement of sigma-1 receptor modulation in the antidepressant action of venlafaxine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Possible involvement of sigma-1 receptors in the anti-immobility action of bupropion, a dopamine reuptake inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Involvement of sigma (sigma1) receptors in modulating the anti-depressant effect of neurosteroids (dehydroepiandrosterone or pregnenolone) in mouse tail-suspension test

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

The sigma receptor as a ligand-regulated auxiliary potassium channel subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Effects of potassium channel inhibitors in the forced swimming test: possible involvement of L-arginine-nitric oxide-soluble guanylate cyclase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

N-methyl-D-aspartate-induced neuronal activation is selectively modulated by sigma receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Sigma 1 receptor subtype is involved in the relief of behavioral despair in the mouse forced swimming test

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Enhanced antidepressant efficacy of sigma1 receptor agonists in rats after chronic intracerebroventricular infusion of beta-amyloid-(1-40) protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Pregnenolone and its sulfate ester in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Neurosteroids: a new brain function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Neurosteroids, neuroactive steroids, and symptoms of affective disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Antidepressant-like effect of the neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice forced swim test.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

The EEG effects of THIP (Gaboxadol) on sleep and waking are mediated by the GABA(A)delta-subunit-containing receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

GABA(A)R plasticity during pregnancy: relevance to postpartum depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

CSF neuroactive steroids in affective disorders: pregnenolone, progesterone, and DBI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Dehydroepiandrosterone in the nucleus accumbens is associated with early onset of depressive-behavior: a study in an animal model of childhood depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Progesterone pretreatment enhances serotonin-stimulated BDNF gene expression in rat c6 glioma cells through production of 5alpha-reduced neurosteroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Sigma (sigma1) receptor mediated anti-depressant-like effects of neurosteroids in the Porsolt forced swim test

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Role of GABA-A and mitochondrial diazepam binding inhibitor receptors in the anti-stress activity of neurosteroids in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

The role of sigma receptors in depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Forebrain afferents to the rat dorsal raphe nucleus demonstrated by retrograde and anterograde tracing methods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Could agomelatine be the ideal antidepressant?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Physiological effects of melatonin: role of melatonin receptors and signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Combination therapy of imipramine and melatonin: additive antidepressant effect in mouse forced swimming test

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-D-aspartate receptors and the L-arginine-nitric oxide pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Melatonin and its agonists: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Agomelatine: a novel mechanism of antidepressant action involving the melatonergic and the serotonergic system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Novel mechanism of antidepressant action: norepinephrine and dopamine disinhibition (NDDI) plus melatonergic agonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Agomelatine treatment of major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

The involvement of glutamate in the pathophysiology of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Acute treatments with GMP produce antidepressant-like effects in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

A double-blind, placebo-controlled study of memantine in the treatment of major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Antidepressant effects of ketamine in depressed patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Lack of persistent effects of ketamine in rodent models of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Effects of lamotrigine on mood in older adults with epilepsy and co-morbid depressive symptoms: an open-label, multicentre, prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Beyond monoamines: glutamatergic function in mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Antidepressant-like effect of folic acid: Involvement of NMDA receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Antidepressants for the new millennium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

AMPA receptors in the therapeutic management of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Enhancement of antidepressant potency by a potentiator of AMPA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Chronic AMPA receptor potentiator (LY451646) treatment increases cell proliferation in adult rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Mood disorders: regulation by metabotropic glutamate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Metabotropic glutamate receptors in the control of mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Increased cell proliferation in the adult mouse hippocampus following chronic administration of group II metabotropic glutamate receptor antagonist, MGS0039.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

5-HT receptor classification and nomenclature: towards a harmonization with the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Effects of the brain-penetrant and selective 5-HT6 receptor antagonist SB-399885 in animal models of anxiety and depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Anxiolytic-like and antidepressant-like effects produced by the selective 5-HT6 receptor antagonist SB-258585 after intrahippocampal administration to rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

5-HT6 receptors: a novel target for cognitive enhancement

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Effect of the selective 5-HT7 receptor antagonist SB 269970 in animal models of anxiety and depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

5-HT7 receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Selective blockade of 5-hydroxytryptamine (5-HT)7 receptors enhances 5-HT transmission, antidepressant-like behavior, and rapid eye movement sleep suppression induced by citalopram in rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

5-HT7 receptor antagonists as a new class of antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

The 5-HT7 receptor influences stereotypic behavior in a model of obsessive-compulsive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Behavioral effects of the beta3 adrenoceptor agonist SR58611A: is it the putative prototype of a new class of antidepressant/anxiolytic drugs?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Confirmation of antidepressant potential of the selective beta3 adrenoceptor agonist amibegron in an animal model of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety and depressive disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Non-peptide vasopressin V1b receptor antagonists as potential drugs for the treatment of stress-related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Evidence that the lateral septum is involved in the antidepressant-like effects of the vasopressin V1b receptor antagonist, SSR149415.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

SSR149415, a non-peptide vasopressin V1b receptor antagonist, has long-lasting antidepressant effects in the olfactory bulbectomy-induced hyperactivity depression model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Antidepressant-like effects of the vasopressin V1b receptor antagonist SSR149415 in the Flinders Sensitive Line rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Mechanism of action of antidepressant drugs: importance of genetically modified mice in the pharmacological in vivo approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Effects of SR48968, a selective non-peptide NK2 receptor antagonist on emotional processes in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Behavioral effects of saredutant, a tachykinin NK2 receptor antagonist, in experimental models of mood disorders under basal and stress-related conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Neurobiology of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Central CRH system in depression and anxiety--evidence from clinical studies with CRH1 receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Glucocorticoid prevents brain-derived neurotrophic factor-mediated maturation of synaptic function in developing hippocampal neurons through reduction in the activity of mitogen-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Antidepressant-like effects of the glucocorticoid receptor antagonist RU-43044 are associated with changes in prefrontal dopamine in mouse models of depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Effects of the selective nonpeptide corticotropin-releasing factor receptor 1 antagonist antalarmin in the chronic mild stress model of depression in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Comparison of the V1b antagonist, SSR149415, and the CRF1 antagonist, CP-154,526, in rodent models of anxiety and depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Anxiolytic- and antidepressant-like profile of a new CRF1 receptor antagonist, R278995/CRA0450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Brain penetrance, receptor occupancy and antistress in vivo efficacy of a small molecule corticotropin releasing factor type I receptor selective antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

The pharmacology of DMP696 and DMP904, non-peptidergic CRF1 receptor antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Antidepressant activity of curcumin: involvement of serotonin and dopamine system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Anti-depressant like effect of curcumin and its combination with piperine in unpredictable chronic stress-induced behavioral, biochemical and neurochemical changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

The antidepressant effects of curcumin in the forced swimming test involve 5-HT1 and 5-HT2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Antidepressant-like effect of rutin isolated from the ethanolic extract from Schinus molle L. in mice: evidence for the involvement of the serotonergic and noradrenergic systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

Allopregnanolone and ganaxolone increase the firing activity of dorsal raphe nucleus serotonergic neurons in female rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780902880850

10.1517/13543780902880850

21 January 2018

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1464083

OpenCitations bibliographic resource ID

1464083

1 reference