Mode of action of cannabinoids on nociceptive nerve endings (Q28238995)

Experimental Brain Research

Europe PubMed Central

title

Mode of action of cannabinoids on nociceptive nerve endings (English)

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Michaela Kress

1

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R Kuner

series ordinal

2

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language of work or name

English

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publication date

June 2009

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published in

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volume

196

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issue

1

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page(s)

79-88

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exact match

https://scigraph.springernature.com/pub.10.1007/s00221-009-1762-0

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cites work

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Delta 9-tetrahydrocannabinol and cannabinol activate capsaicin-sensitive sensory nerves via a CB1 and CB2 cannabinoid receptor-independent mechanism.

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A decrease in anandamide signaling contributes to the maintenance of cutaneous mechanical hyperalgesia in a model of bone cancer pain

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Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibers and adnexal structures in human skin

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Molecular characterization of a peripheral receptor for cannabinoids

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The cloned capsaicin receptor integrates multiple pain-producing stimuli

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Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

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Localisation of cannabinoid receptor 1 in rat dorsal root ganglion using in situ hybridisation and immunohistochemistry

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Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity

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Peripheral cannabinoids attenuate carcinoma-induced nociception in mice

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Effects of Anandamide and Noxious Heat on Intracellular Calcium Concentration in Nociceptive DRG Neurons of Rats

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Cannabinoids desensitize capsaicin and mustard oil responses in sensory neurons via TRPA1 activation

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Cannabinoids attenuate depolarization-dependent Ca2+ influx in intermediate-size primary afferent neurons of adult rats

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Cannabinoid CB2 receptor-mediated anti-nociception in models of acute and chronic pain

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Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line

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Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees

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Cannabinoid modulation of cutaneous Adelta nociceptors during inflammation

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The orphan receptor GPR55 is a novel cannabinoid receptor

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Localisation of cannabinoid CB(1) receptor immunoreactivity in the guinea pig and rat myenteric plexus

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Differential effects of CB1 and opioid agonists on two populations of adult rat dorsal root ganglion neurons.

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Cannabinoid receptor signaling.

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Inhibitory effects of CB1 and CB2 receptor agonists on responses of DRG neurons and dorsal horn neurons in neuropathic rats

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A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation

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Role of ionotropic cannabinoid receptors in peripheral antinociception and antihyperalgesia

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The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain

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Functional role of high-affinity anandamide transport, as revealed by selective inhibition

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Endocannabinoids: synthesis and degradation

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Localization of central cannabinoid CB1 receptor messenger RNA in neuronal subpopulations of rat dorsal root ganglia: a double-label in situ hybridization study.

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Peripheral cannabinoid CB1 receptors inhibit evoked responses of nociceptive neurones in vivo

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The cannabinoid WIN 55,212-2 inhibits transient receptor potential vanilloid 1 (TRPV1) and evokes peripheral antihyperalgesia via calcineurin

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Formation and inactivation of endogenous cannabinoid anandamide in central neurons

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CB1 cannabinoid receptors and on-demand defense against excitotoxicity

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12 December 2020

Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels

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An amino-terminal variant of the central cannabinoid receptor resulting from alternative splicing

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12 December 2020

Further evidence for the existence of a specific process for the membrane transport of anandamide

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12 December 2020

Identification of a region in the TASK3 two pore domain potassium channel that is critical for its blockade by methanandamide.

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12 December 2020

Induction of CB1 cannabinoid receptor by inflammation in primary afferent neurons facilitates antihyperalgesic effect of peripheral CB1 agonist

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12 December 2020

Activation of the cannabinoid 2 (CB2) receptor inhibits murine mesenteric afferent nerve activity

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12 December 2020

Cannabinoid WIN 55,212-2 regulates TRPV1 phosphorylation in sensory neurons

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12 December 2020

Actions of cannabinoid receptor ligands on rat cultured sensory neurones: implications for antinociception

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12 December 2020

CB2 cannabinoid receptor mediation of antinociception.

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12 December 2020

Activation of cannabinoid CB2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation

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12 December 2020

Cannabinoid mechanisms of pain suppression.

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12 December 2020

The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins.

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12 December 2020

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

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12 December 2020

Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8.

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12 December 2020

In vitro and in vivo characterization of A-796260: a selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models

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12 December 2020

Activation of peripheral cannabinoid CB1 receptors inhibits mechanically evoked responses of spinal neurons in noninflamed rats and rats with hindpaw inflammation

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12 December 2020

Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation.

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12 December 2020

Anandamide effects on 5-HT(3) receptors in vivo

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12 December 2020

Co-expression of the voltage-gated potassium channel Kv1.4 with transient receptor potential channels (TRPV1 and TRPV2) and the cannabinoid receptor CB1 in rat dorsal root ganglion neurons

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12 December 2020

CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids

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12 December 2020

The endocannabinoid system as an emerging target of pharmacotherapy

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12 December 2020

Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS

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12 December 2020

Cannabinoid CB2 receptor: a new target for controlling neural cell survival?

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12 December 2020

GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

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12 December 2020

A unified nomenclature for the superfamily of TRP cation channels.

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12 December 2020

TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents

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12 December 2020

The agonists for nociceptors are ubiquitous, but the modulators are specific: P2X receptors in the sensory neurons are modulated by cannabinoids

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12 December 2020

Inhibitory activity of the novel CB2 receptor agonist, GW833972A, on guinea-pig and human sensory nerve function in the airways

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12 December 2020

A capsaicin-receptor homologue with a high threshold for noxious heat

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12 December 2020

The capsaicin receptor: a heat-activated ion channel in the pain pathway

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12 December 2020

Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

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12 December 2020

The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1.

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12 December 2020

Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons.

1 reference

12 December 2020