Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signaling (Q28237281)

4

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Paulo De Sepulveda

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Sébastien Letard

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author name string

Julie Bayle

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Ronald Frank

Journal of Biological Chemistry

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language of work or name

English

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publication date

26 March 2004

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published in

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volume

279

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page(s)

12249-59

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issue

13

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cites work

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Negative regulation of cytokine signaling: STAT-induced STAT inhibitor

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Negative regulation of cytokine signaling pathways

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Twenty proteins containing a C-terminal SOCS box form five structural classes

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Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice

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Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

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Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.

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Gigantism in mice lacking suppressor of cytokine signalling-2

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Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2

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SOCS3 is essential in the regulation of fetal liver erythropoiesis

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Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3

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SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation

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A family of cytokine-inducible inhibitors of signalling

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Structure and function of a new STAT-induced STAT inhibitor

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A new protein containing an SH2 domain that inhibits JAK kinases

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The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

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The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

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The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

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Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.

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CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2

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SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

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Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

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SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

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SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation

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Cloning and characterization of novel CIS family genes

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The SOCS box: a tale of destruction and degradation

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Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation

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Suppressor of cytokine signaling 1 interacts with the macrophage colony-stimulating factor receptor and negatively regulates its proliferation signal

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Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor

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Identification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT) activation

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SOCS-3 is an insulin-induced negative regulator of insulin signaling

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Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance

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Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

21 January 2018

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Critical roles of c-Kit tyrosine residues 567 and 719 in stem cell factor-induced chemotaxis: contribution of src family kinase and PI3-kinase on calcium mobilization and cell migration

21 January 2018

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SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain

21 January 2018

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Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction

21 January 2018

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Direct association of Csk homologous kinase (CHK) with the diphosphorylated site Tyr568/570 of the activated c-KIT in megakaryocytes

21 January 2018

1 reference

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The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-Kit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313381200

Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

21 January 2018

1 reference

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Regulation of the mitogen-activated protein kinase signaling pathway by SHP2.

21 January 2018

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SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities

21 January 2018

1 reference

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release_foa7osmw7bhjtj46vb6hnjhfmq

21 January 2018

Identifiers

DOI

10.1074/JBC.M313381200

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Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/foa7osmw7bhjtj46vb6hnjhfmq