Queuosine deficiency in eukaryotes compromises tyrosine production through increased tetrahydrobiopterin oxidation (Q28235401)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21487017%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Queuosine deficiency in eukaryotes compromises tyrosine production through increased tetrahydrobiopterin oxidation (English)

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28 January 2020

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ChEBI release 2020-05-28

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2

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28 January 2020

Vincent P. Kelly

6

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28 January 2020

author name string

Tatsiana Rakovich

1

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28 January 2020

Ilana Bernstein

3

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28 January 2020

Vimbai M Chikwana

4

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28 January 2020

Dirk Iwata-Reuyl

5

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28 January 2020

language of work or name

English

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publication date

12 April 2011

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Journal of Biological Chemistry

28 January 2020

published in

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28 January 2020

volume

286

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28 January 2020

issue

22

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28 January 2020

page(s)

19354-19363

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Activation of phenylalanine hydroxylase induces positive cooperativity toward the natural cofactor

28 January 2020

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Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways

20 March 2017

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Improvement of reading frame maintenance is a common function for several tRNA modifications

20 March 2017

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Queuosine modification of the wobble base in tRNAHis influences 'in vivo' decoding properties

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Queuosine formation in eukaryotic tRNA occurs via a mitochondria-localized heteromeric transglycosylase

20 March 2017

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Comparative activity of rat liver dihydrofolate reductase with 7,8-dihydrofolate and other 7,8-dihydropteridines

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20 March 2017

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Delivery of exogenous tetrahydrobiopterin (BH4) to cells of target organs: role of salvage pathway and uptake of its precursor in effective elevation of tissue BH4.

29 September 2017

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The distal sequence element of the selenocysteine tRNA gene is a tissue-dependent enhancer essential for mouse embryogenesis

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Some metabolic relationships between biopterin and folate: Implications for the ?methyl trap hypothesis?

29 September 2017

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Trans-dominant inhibition of transcription activator LFB1

29 September 2017

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29 September 2017

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Identifying inhibitors of queuine modification of tRNA in cultured cells

29 September 2017

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Tetrahydrobiopterin is synthesized from 6-pyruvoyl-tetrahydropterin by the human aldo-keto reductase AKR1 family members

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Comparison of epidermal keratinocytes and dermal fibroblasts as potential target cells for somatic gene therapy of phenylketonuria

21 January 2018

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Tetrahydrobiopterin uptake in supplemental administration: elevation of tissue tetrahydrobiopterin in mice following uptake of the exogenously oxidized product 7,8-dihydrobiopterin and subsequent reduction by an anti-folate-sensitive process

21 January 2018

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Identification and validation of PDGF transcriptional targets by microarray-coupled gene-trap mutagenesis.

21 January 2018

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Diet-dependent depletion of queuosine in tRNAs in Caenorhabditis elegans does not lead to a developmental block

21 January 2018

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Queuine promotes antioxidant defence system by activating cellular antioxidant enzyme activities in cancer

21 January 2018

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Tetrahydrobiopterin protects phenylalanine hydroxylase activity in vivo: implications for tetrahydrobiopterin-responsive hyperphenylalaninemia

21 January 2018

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Wild-type phenylalanine hydroxylase activity is enhanced by tetrahydrobiopterin supplementation in vivo: an implication for therapeutic basis of tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency

21 January 2018

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Plasma tetrahydrobiopterin/dihydrobiopterin ratio: a possible marker of endothelial dysfunction

21 January 2018

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Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension

21 January 2018

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Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice

21 January 2018

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Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function.

21 January 2018

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The autoxidation of tetrahydrobiopterin revisited. Proof of superoxide formation from reaction of tetrahydrobiopterin with molecular oxygen

21 January 2018

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Modulation of lactate dehydrogenase isozymes by modified base queuine.

21 January 2018

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The effect of queuosine on tRNA structure and function.

21 January 2018

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Specific interaction of the diastereomers 7(R)- and 7(S)-tetrahydrobiopterin with phenylalanine hydroxylase: implications for understanding primapterinuria and vitiligo

21 January 2018

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Effects of a diet deficient in tyrosine and queuine on germfree mice

21 January 2018

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12 December 2020

Transfer RNA modification, temperature and DNA superhelicity have a common target in the regulatory network of the virulence of Shigella flexneri: the expression of the virF gene

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12 December 2020

Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats

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12 December 2020

Substrate activation of phenylalanine hydroxylase. A kinetic characterization

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12 December 2020

Effect of diet on the queuosine family of tRNAs of germ-free mice

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12 December 2020

Administration of exogenous queuine is essential for the biosynthesis of the queuosine-containing transfer RNAs in the mouse

1 reference

12 December 2020

Queuine, a modified base incorporated posttranscriptionally into eukaryotic transfer RNA: wide distribution in nature

1 reference

12 December 2020

Dictyostelium discoideum: a useful model system to evaluate the function of queuine and of the Q-family of tRNAs

1 reference

12 December 2020

Substrate and inhibitor specificity of tRNA-guanine ribosyltransferase

1 reference

12 December 2020

1 reference

12 December 2020

Possible involvement of queuine in oxidative metabolism

1 reference

12 December 2020

The deazaguanine-derivative, queuine, affects cell proliferation, protein phosphorylation and the expression of the proto oncogenes c-fos and c-myc in HeLa cells

1 reference

12 December 2020

Possible involvement of queuine in control mechanisms of protein synthesis and protein phosphorylation in eukaryotes

1 reference

12 December 2020

The nutrient factor queuine protects HeLa cells from hypoxic stress and improves metabolic adaptation to oxygen availability.

1 reference

12 December 2020

Regulation of rat liver phenylalanine hydroxylase. III. Control of catalysis by (6R)-tetrahydrobiopterin and phenylalanine

1 reference

12 December 2020

Regulation of signalling by receptor tyrosine kinases in HeLa cells involves the q-base

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12 December 2020

Identifiers

DOI

10.1074/JBC.M111.219576

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21487017%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21487017%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

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