Overloading of stable and exclusion of unstable human superoxide dismutase-1 variants in mitochondria of murine amyotrophic lateral sclerosis models (Q28235353)

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scientific article (publication date: 19 April 2006)

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English	Overloading of stable and exclusion of unstable human superoxide dismutase-1 variants in mitochondria of murine amyotrophic lateral sclerosis models	scientific article (publication date: 19 April 2006)

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scholarly article

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Overloading of stable and exclusion of unstable human superoxide dismutase-1 variants in mitochondria of murine amyotrophic lateral sclerosis models (English)

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Europe PubMed Central

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11 May 2020

amyotrophic lateral sclerosis

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inferred from title

Peter M Andersen

4

object named as

Peter M Andersen

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author name string

Daniel Bergemalm

1

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11 May 2020

P Andreas Jonsson

2

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11 May 2020

Karin S Graffmo

3

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11 May 2020

Thomas Brännström

5

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11 May 2020

Anna Rehnmark

6

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11 May 2020

Stefan L Marklund

7

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11 May 2020

Peter M Andersen

4

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11 May 2020

language of work or name

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publication date

19 April 2006

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Journal of Neuroscience

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11 May 2020

26

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11 May 2020

16

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11 May 2020

4147-4154

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11 May 2020

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

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https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mut

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https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations

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https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS

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https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High molecular weight complexes of mutant superoxide dismutase 1: age-dependent and tissue-specific accumulation

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https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

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https://pubmed.ncbi.nlm.nih.gov/16624935

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Amyotrophic lateral sclerosis: a proposed mechanism

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https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectrophotometric study of spontaneous disproportionation of superoxide anion radical and sensitive direct assay for superoxide dismutase

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https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors controlling the uptake of yeast copper/zinc superoxide dismutase into mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Copper,zinc superoxide dismutase is primarily a cytosolic protein in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sixteen novel mutations in the Cu/Zn superoxide dismutase gene in amyotrophic lateral sclerosis: a decade of discoveries, defects and disputes

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https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome c association with the inner mitochondrial membrane is impaired in the CNS of G93A-SOD1 mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low levels of ALS-linked Cu/Zn superoxide dismutase increase the production of reactive oxygen species and cause mitochondrial damage and death in motor neuron-like cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apaf1 mediates apoptosis and mitochondrial damage induced by mutant human SOD1s typical of familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial superoxide simutase. Site of synthesis and intramitochondrial localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural history of amyotrophic lateral sclerosis in a database population. Validation of a scoring system and a model for survival prediction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal binding and reactivity of copper in mutant superoxide dismutase isolated from amyotrophic lateral sclerosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5461-05.2006

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673995&resulttype=core&format=json

11 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673995&resulttype=core&format=json

11 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673995&resulttype=core&format=json

11 May 2020

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