Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice (Q28235182)

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1 January 2020

title

Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice (English)

1 reference

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1 January 2020

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14

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1 January 2020

author name string

Urvi Desai

1

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1 January 2020

E-Chiang Lee

2

1 reference

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1 January 2020

Kyu Chung

3

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1 January 2020

Cuihua Gao

4

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1 January 2020

Jason Gay

5

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1 January 2020

Billie Key

6

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1 January 2020

Gwenn Hansen

7

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1 January 2020

Dennis Machajewski

8

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1 January 2020

Kenneth A Platt

9

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1 January 2020

Arthur T Sands

10

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1 January 2020

Matthias Schneider

11

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1 January 2020

Isaac Van Sligtenhorst

12

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1 January 2020

Adisak Suwanichkul

13

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1 January 2020

Nat Wilganowski

15

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1 January 2020

June Wingert

16

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1 January 2020

Brian P Zambrowicz

17

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1 January 2020

Greg Landes

18

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1 January 2020

David R Powell

19

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1 January 2020

language of work or name

English

0 references

publication date

3 July 2007

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Proceedings of the National Academy of Sciences of the United States of America

1 January 2020

published in

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volume

104

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1 January 2020

issue

28

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1 January 2020

page(s)

11766-11771

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Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice

1 January 2020

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Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN

20 March 2017

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Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation

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Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene

20 March 2017

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ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase

20 March 2017

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Differential regulation and properties of angiopoietin-like proteins 3 and 4

20 March 2017

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Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

20 March 2017

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Angiopoietin-like protein 4 is a potent hyperlipidemia-inducing factor in mice and inhibitor of lipoprotein lipase

20 March 2017

1 reference

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Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL.

20 March 2017

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Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor

29 September 2017

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Obesity drugs and their targets: correlation of mouse knockout phenotypes with drug effects in vivo

29 September 2017

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The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity

29 September 2017

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Inhibition of cardiac lipoprotein utilization by transgenic overexpression of Angptl4 in the heart.

29 September 2017

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Predicting drug efficacy: knockouts model pipeline drugs of the pharmaceutical industry

29 September 2017

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Construction of gene targeting vectors from lambda KOS genomic libraries

29 September 2017

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Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells

29 September 2017

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Oligomerization state-dependent hyperlipidemic effect of angiopoietin-like protein 4.

29 September 2017

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Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism.

21 January 2018

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ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis.

21 January 2018

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Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

21 January 2018

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Knockouts model the 100 best-selling drugs--will they model the next 100?

21 January 2018

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Plasma triglycerides and type III hyperlipidemia are independently associated with premature familial coronary artery disease

21 January 2018

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Alteration of lipid profiles in plasma of transgenic mice expressing human lipoprotein lipase.

21 January 2018

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Transgenic mice expressing human lipoprotein lipase driven by the mouse metallothionein promoter. A phenotype associated with increased perinatal mortality and reduced plasma very low density lipoprotein of normal size

27 November 2018

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Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study. Implications for treatment

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17609370

12 December 2020

inferred from PubMed ID database lookup

Induced mutant mice expressing lipoprotein lipase exclusively in muscle have subnormal triglycerides yet reduced high density lipoprotein cholesterol levels in plasma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17609370

12 December 2020

inferred from PubMed ID database lookup

Rapid development of glomerular injury and renal failure in mice lacking p53R2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17609370

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0705041104

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17609370%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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https://api.fatcat.wiki/v0/release/tyllolmmxfaidojt7zmofk3x3e

24 November 2022

mapped directly with Wikidata item

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17609370%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

2 references