Splicing regulation at the second catalytic step by Sex-lethal involves 3' splice site recognition by SPF45 (Q28217970)

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Angus Lamond

object named as

Angus I Lamond

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author name string

María José Lallena

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Kevin J Chalmers

Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry

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language of work or name

English

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publication date

3 May 2002

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published in

Cell

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volume

109

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page(s)

285-96

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issue

3

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cites work

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SLU7 and a novel activity, SSF1, act during the PRP16-dependent step of yeast pre-mRNA splicing.

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Positive autoregulation of sex-lethal by alternative splicing maintains the female determined state in Drosophila.

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Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors

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Evidence for a linear search in bimolecular 3' splice site AG selection

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Evidence that U5 snRNP recognizes the 3' splice site for catalytic step II in mammals

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The RNA splicing factor hSlu7 is required for correct 3' splice-site choice

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Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing

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An upstream AG determines whether a downstream AG is selected during catalytic step II of splicing

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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An essential splicing factor, SLU7, mediates 3' splice site choice in yeast

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Modulation of msl-2 5' splice site recognition by Sex-lethal

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Targeting of U2AF65 to sites of active splicing in the nucleus

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Polyoma virus small tumor antigen pre-mRNA splicing requires cooperation between two 3' splice sites

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Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

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Alternative splicing: increasing diversity in the proteomic world

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Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein

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Pre-mRNA splicing in the new millennium

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Sex-lethal autoregulation requires multiple cis-acting elements upstream and downstream of the male exon and appears to depend largely on controlling the use of the male exon 5' splice site

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Binding of the Drosophila Sex-lethal gene product to the alternative splice site of transformer primary transcript

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Characterization and functional ordering of Slu7p and Prp17p during the second step of pre-mRNA splicing in yeast

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Expression of msl-2 causes assembly of dosage compensation regulators on the X chromosomes and female lethality in Drosophila

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The role of branchpoint-3' splice site spacing and interaction between intron terminal nucleotides in 3' splice site selection in Saccharomyces cerevisiae

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Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG.

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Intron recognition comes of AGe

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Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites

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Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

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Switch in 3' splice site recognition between exon definition and splicing catalysis is important for sex-lethal autoregulation.

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The organization of 3' splice-site sequences in mammalian introns

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Alternative branch points are selected during splicing of a yeast pre-mRNA in mammalian and yeast extracts

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Control of Drosophila Sex-lethal pre-mRNA splicing by its own female-specific product

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Alterations of RNase H sensitivity of the 3′ splice site region during thein vitrosplicing reaction

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PRP16 is an RNA-dependent ATPase that interacts transiently with the spliceosome

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Alternative pre-mRNA splicing: the logic of combinatorial control

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Scanning from an independently specified branch point defines the 3' splice site of mammalian introns

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Scanning and competition between AGs are involved in 3' splice site selection in mammalian introns

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Sex-specific alternative splicing of RNA from the transformer gene results from sequence-dependent splice site blockage

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7 January 2021

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The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA.

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The Sex-lethal amino terminus mediates cooperative interactions in RNA binding and is essential for splicing regulation.

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Identification of a human protein that recognizes the 3' splice site during the second step of pre-mRNA splicing

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Diffusion mechanisms in metallic supercooled liquids and glasses

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Cloning and domain structure of the mammalian splicing factor U2AF

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The conserved dinucleotide AG of the 3' splice site may be recognized twice during in vitro splicing of mammalian mRNA precursors

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Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles

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Both subunits of U2AF recognize the 3' splice site in Caenorhabditis elegans.

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7 January 2021

The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing

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