CD40:CD40L interactions in X-linked and non-X-linked hyper-IgM syndromes (Q28216904)

TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling

Europe PubMed Central

title

CD40:CD40L interactions in X-linked and non-X-linked hyper-IgM syndromes (English)

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author name string

A Bhushan

series ordinal

1

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L R Covey

series ordinal

2

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language of work or name

English

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publication date

2001

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published in

Immunologic Research

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volume

24

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issue

3

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page(s)

311-24

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cites work

1 reference

12 December 2020

Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection.

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12 December 2020

Immunoglobulin class switching

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12 December 2020

Immune regulation by CD40 and its ligand GP39.

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12 December 2020

A novel RING finger protein interacts with the cytoplasmic domain of CD40

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12 December 2020

Clinical spectrum of X-linked hyper-IgM syndrome

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12 December 2020

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes

1 reference

12 December 2020

Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM

1 reference

12 December 2020

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

12 December 2020

Immunologic studies of three family members with the immunodeficiency with hyper-IgM syndrome

1 reference

12 December 2020

Stimulation of protein tyrosine phosphorylation, phosphoinositide turnover, and multiple previously unidentified serine/threonine-specific protein kinases by the Pan-B-cell receptor CD40/Bp50 at discrete developmental stages of human B-cell ontogeny

1 reference

12 December 2020

Mitogen- and IL-4-regulated expression of germ-line Ig gamma 2b transcripts: evidence for directed heavy chain class switching

1 reference

12 December 2020

CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

1 reference

12 December 2020

Epstein-barr virus transformation: involvement of latent membrane protein 1-mediated activation of NF-kappaB.

1 reference

12 December 2020

Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells

1 reference

12 December 2020

Switch transcripts in immunoglobulin class switching

1 reference

12 December 2020

Hyper IgM syndrome associated with defective CD40-mediated B cell activation

1 reference

12 December 2020

A transcriptional defect underlies B lymphocyte dysfunction in a patient diagnosed with non-X-linked hyper-IgM syndrome

1 reference

12 December 2020

CD40 and its ligand in host defense

1 reference

12 December 2020

gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory

1 reference

12 December 2020

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

12 December 2020

Molecular structure of human lymphocyte receptor for immunoglobulin E

1 reference

12 December 2020

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1 reference

12 December 2020

Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.

1 reference

12 December 2020

CD40 ligand and its role in X-linked hyper-IgM syndrome

1 reference

12 December 2020

CD40Lbase: a database of CD40L gene mutations causing X-linked hyper-IgM syndrome

1 reference

12 December 2020

Mapping of the X-linked form of hyper-IgM syndrome (HIGM1) to Xq26 by close linkage to HPRT

1 reference

12 December 2020

Common variable immunodeficiency: clinical and immunological features of 248 patients.

1 reference

12 December 2020

Impaired T cell-mediated macrophage activation in CD40 ligand-deficient mice

1 reference

12 December 2020

A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon

1 reference

12 December 2020

CD40 ligand is required for protective cell-mediated immunity to Leishmania major

1 reference

12 December 2020

CD40 ligand and appropriate cytokines induce switching to IgG, IgA, and IgE and coordinated germinal center and plasmacytoid phenotypic differentiation in a human monoclonal IgM+IgD+ B cell line.

1 reference

12 December 2020

Humoral immune responses in CD40 ligand-deficient mice

1 reference

12 December 2020

1 reference

12 December 2020

Clinical and immunologic analyses of 103 patients with common variable immunodeficiency

1 reference

12 December 2020

Evidence that in X-linked immunodeficiency with hyperimmunoglobulinemia M the intrinsic immunoglobulin heavy chain class switch mechanism is intact

1 reference

12 December 2020

CD40-triggered protein tyrosine phosphorylation on Vav and on phosphatidylinositol 3-kinase correlates with survival of the Ramos-Burkitt lymphoma B cell line

1 reference

12 December 2020

Human malignant T cells capable of inducing an immunoglobulin class switch

1 reference

12 December 2020

Hypogammaglobulinemia in mother and son

1 reference

12 December 2020

A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO)

1 reference

12 December 2020

The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family

1 reference

12 December 2020

B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching

1 reference

12 December 2020

The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity

1 reference

12 December 2020

The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells.

1 reference

12 December 2020

Stimulation of CD40 with purified soluble gp39 induces proinflammatory responses in human monocytes

1 reference

12 December 2020

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

12 December 2020

Mice deficient for the CD40 ligand

1 reference

12 December 2020

B cell differentiation defects in common variable immunodeficiency are ameliorated after stimulation with anti-CD40 antibody and IL-10

1 reference

12 December 2020

Structure and expression of murine germ-line immunoglobulin epsilon heavy chain transcripts induced by interleukin 4.

1 reference

12 December 2020

Phosphatidylinositol 3-kinase activation in normal human B lymphocytes

1 reference

12 December 2020

CD40 ligand (CD40L) expression and B cell function in agammaglobulinemia with normal or elevated levels of IgM (HIM). Comparison of X-linked, autosomal recessive, and non-X-linked forms of the disease, and obligate carriers

1 reference

12 December 2020

Abnormal B cell differentiation and variable increased T cell suppression in immunodeficiency with hyper-IgM

1 reference

12 December 2020

Ligation of CD40 induces sterile transcripts of multiple Ig H chain isotypes in human B cells

1 reference

12 December 2020

Identification of a novel surface protein on activated CD4+ T cells that induces contact-dependent B cell differentiation (help)

1 reference

12 December 2020

Activated T cells induce interleukin-12 production by monocytes via CD40-CD40 ligand interaction

1 reference

12 December 2020

CD40 ligand is required for resolution of Pneumocystis carinii pneumonia in mice

1 reference

12 December 2020

The immunoglobulin class switch: beyond "accessibility".

1 reference

12 December 2020

Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal

1 reference

12 December 2020

Defective antigen-induced lymphocyte proliferation in the X-linked hyper-IgM syndrome

1 reference

12 December 2020

Cytokine regulation of immunoglobulin isotype switching and expression.

1 reference

12 December 2020

X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling

1 reference

12 December 2020

Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity

1 reference

12 December 2020

Processing of switch transcripts is required for targeting of antibody class switch recombination

1 reference

12 December 2020

Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene

1 reference

12 December 2020

Involvement of CRAF1, a relative of TRAF, in CD40 signaling

1 reference

12 December 2020

Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia

1 reference

12 December 2020

Immunohistologic analysis of ineffective CD40-CD40 ligand interaction in lymphoid tissues from patients with X-linked immunodeficiency with hyper-IgM. Abortive germinal center cell reaction and severe depletion of follicular dendritic cells.

1 reference

12 December 2020

Hyper IgM immunodeficiency. A primary dysfunction of B lymphocyte isotype switching

1 reference

12 December 2020

Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand

1 reference

12 December 2020

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

1 reference

12 December 2020

IgM-restricted production of immunoglobulin by lymphoid cell lines from patients with immunodeficiency with hyper IgM (dysgammaglobulinemia).

1 reference

12 December 2020

Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2

1 reference

12 December 2020

The p27 catalytic subunit of the apolipoprotein B mRNA editing enzyme is a cytidine deaminase.

1 reference

12 December 2020

Structure and expression of germ line immunoglobulin heavy-chain epsilon transcripts: interleukin-4 plus lipopolysaccharide-directed switching to C epsilon

1 reference

12 December 2020

A membrane protein encoded by Epstein-Barr virus in latent growth-transforming infection

1 reference

12 December 2020

Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction

1 reference

12 December 2020

Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling

1 reference

12 December 2020

Nucleotide sequence of an mRNA transcribed in latent growth-transforming virus infection indicates that it may encode a membrane protein

1 reference

12 December 2020

The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation

1 reference

12 December 2020

The CD5/CD72 receptor system is coexpressed with several functionally relevant counterstructures on human B cells and delivers a critical signaling activity

1 reference

12 December 2020

CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome

1 reference

12 December 2020

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

12 December 2020

Mutations of the CD40 ligand gene and its effect on CD40 ligand expression in patients with X-linked hyper IgM syndrome.

1 reference

12 December 2020

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

1 reference

12 December 2020

A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40

1 reference

12 December 2020

RNA splicing generates alternate forms of germline immunoglobulin alpha heavy chain transcripts

1 reference

12 December 2020

IL-4 plus CD40 monoclonal antibody induces human B cells gamma subclass-specific isotype switch: switching to gamma 1, gamma 3, and gamma 4, but not gamma 2.

1 reference

12 December 2020

Structure and expression of germline immunoglobulin gamma 3 heavy chain gene transcripts: implications for mitogen and lymphokine directed class-switching

1 reference

12 December 2020

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

1 reference

12 December 2020

Differentiation Capacity of Cultured B Lymphocytes from Immunodeficient Patients

1 reference

12 December 2020

Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes

1 reference

12 December 2020

Molecular characterization of germ-line immunoglobulin A transcripts produced during transforming growth factor type beta-induced isotype switching

1 reference

12 December 2020

Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM

1 reference

12 December 2020

Abnormal CD40-mediated activation pathway in B lymphocytes from patients with hyper-IgM syndrome and normal CD40 ligand expression

1 reference

12 December 2020

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

12 December 2020

The CD40 antigen and its ligand

1 reference

12 December 2020

Molecular and biological characterization of a murine ligand for CD40

1 reference

12 December 2020

Normal CD40-mediated activation of monocytes and dendritic cells from patients with hyper-IgM syndrome due to a CD40 pathway defect in B cells

1 reference

12 December 2020

A Family with Several Cases of Hypogammaglobulinaemia

1 reference

12 December 2020

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions

1 reference

12 December 2020

Hyper immunoglobulin M immunodeficiency. (Dysgammaglobulinemia). Presence of immunoglobulin M-secreting plasmacytoid cells in peripheral blood and failure of immunoglobulin M-immunoglobulin G switch in B-cell differentiation

1 reference

12 December 2020

CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40.

1 reference

12 December 2020

Isolation of full-length cDNA and chromosomal localization of human NF-kappaB modulator NEMO to Xq28

1 reference

12 December 2020

Mutations in activation-induced cytidine deaminase in patients with hyper IgM syndrome

1 reference

12 December 2020

S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process

1 reference

12 December 2020

Polyclonal immunoglobulin secretion in patients with common variable immunodeficiency using monoclonal B cell differentiation factors

1 reference

12 December 2020

Molecular interactions mediating T-B lymphocyte collaboration in human lymphoid follicles. Roles of T cell-B-cell-activating molecule (5c8 antigen) and CD40 in contact-dependent help

1 reference

12 December 2020

Induction by anti-CD40 antibody or soluble CD40 ligand and cytokines of IgG, IgA and IgE production by B cells from patients with X-linked hyper IgM syndrome

1 reference

12 December 2020

CD40L: a multi-functional ligand

1 reference

12 December 2020

Immunodeficiency with hyper-IgM (HIM)

1 reference

12 December 2020

Activated B cells from patients with common variable immunodeficiency proliferate and synthesize immunoglobulin

1 reference

12 December 2020

Evidence for a defect in "switch" T cells in patients with immunodeficiency and hyperimmunoglobulinemia M

1 reference

12 December 2020

T cell clones from an X-linked hyper-immunoglobulin (IgM) patient induce IgE synthesis in vitro despite expression of nonfunctional CD40 ligand

1 reference

12 December 2020

Induction of the transcription factors NF-kappa B, AP-1 and NF-AT during B cell stimulation through the CD40 receptor

1 reference

12 December 2020

Biosynthesis and secretion of immunoglobulins by peripheral-blood lymphocytes in severe hypogammaglobulinaemia.

1 reference

12 December 2020

Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation

1 reference

12 December 2020

Isolation of Full-Length cDNA and Chromosomal Localization of Human NF-κB Modulator NEMO to Xq28

1 reference

12 December 2020