Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex (Q28215094)

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10 November 2019

title

Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex (English)

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10 November 2019

1

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10 November 2019

Noel F. Lowndes

series ordinal

3

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10 November 2019

author name string

C Gilbert

series ordinal

2

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10 November 2019

language of work or name

English

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publication date

1 September 2001

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10 November 2019

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10 November 2019

volume

3

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10 November 2019

page(s)

844-847

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10 November 2019

issue

9

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https://scigraph.springernature.com/pub.10.1038/ncb0901-844

10 November 2019

exact match

0 references

cites work

The many interfaces of Mre11

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

A novel role for the budding yeast RAD9 checkpoint gene in DNA damage-dependent transcription.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

MEC1-dependent phosphorylation of Rad9p in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

DNA damage checkpoints update: getting molecular

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Sensing and responding to DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Complex formation and functional versatility of Mre11 of budding yeast in recombination

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

In situ visualization of DNA double-strand break repair in human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1- and Rad53-dependent checkpoint in budding yeast

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Radiation induction of p53 in cells from Nijmegen breakage syndrome is defective but not similar to ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Impaired p53-mediated DNA damage response, cell-cycle disturbance and chromosome aberrations in Nijmegen breakage syndrome lymphoblastoid cell lines.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Chromosomal sensitivity to clastogenic agents and cell cycle perturbations in Nijmegen breakage syndrome lymphoblastoid cell lines.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

G2 repair in Nijmegen breakage syndrome: G2 duration and effect of caffeine and cycloheximide in control and X-ray irradiated lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0901-844

7 January 2021

Identifiers

DOI

10.1038/NCB0901-844

2 references

Consolidated OpenCitations Corpus – April 2017

2339291

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11533665%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 November 2019

1020395336

0 references

2339291

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

2339291