microRNAs: tiny regulators with great potential (Q28214699)

Role for a bidentate ribonuclease in the initiation step of RNA interference

Europe PubMed Central

title

microRNAs: tiny regulators with great potential (English)

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1 reference

V Ambros

1

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language of work or name

English

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publication date

28 December 2001

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published in

Cell

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volume

107

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page(s)

823-6

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issue

7

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cites work

1 reference

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RNA interference is mediated by 21- and 22-nucleotide RNAs

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Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

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Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

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Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

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Identification of novel genes coding for small expressed RNAs

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An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

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An extensive class of small RNAs in Caenorhabditis elegans

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

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The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA

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The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

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Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

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Control of developmental timing in animals

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The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor

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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

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