Grb4/Nckbeta acts as a nuclear repressor of v-Abl-induced transcription from c-jun/c-fos promoter elements (Q28213938)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11514578%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Grb4/Nckbeta acts as a nuclear repressor of v-Abl-induced transcription from c-jun/c-fos promoter elements (English)

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10 November 2019

4

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10 November 2019

author name string

Jahn T

1

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10 November 2019

Seipel P

2

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10 November 2019

Coutinho S

3

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10 November 2019

Peschel C

5

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10 November 2019

Duyster J

6

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10 November 2019

language of work or name

English

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publication date

20 August 2001

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Journal of Biological Chemistry

10 November 2019

published in

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10 November 2019

volume

276

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10 November 2019

issue

46

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10 November 2019

page(s)

43419-43427

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SH2 and SH3-containing adaptor proteins: redundant or independent mediators of intracellular signal transduction.

10 November 2019

cites work

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Identification of Nck family genes, chromosomal localization, expression, and signaling specificity

21 January 2018

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Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck

21 January 2018

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Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways

21 January 2018

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Nck recruitment to Eph receptor, EphB1/ELK, couples ligand activation to c-Jun kinase

21 January 2018

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NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

21 January 2018

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Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation

21 January 2018

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The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway

21 January 2018

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Binding of NCK to SOS and activation of ras-dependent gene expression

21 January 2018

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Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

21 January 2018

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Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

21 January 2018

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The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels

21 January 2018

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Nckbeta adapter regulates actin polymerization in NIH 3T3 fibroblasts in response to platelet-derived growth factor bb

21 January 2018

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Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions

21 January 2018

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AP-1 function and regulation

21 January 2018

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The regulation of AP-1 activity by mitogen-activated protein kinases

21 January 2018

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Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

21 January 2018

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Degradation of c-Fos by the 26S proteasome is accelerated by c-Jun and multiple protein kinases

21 January 2018

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A new group of conserved coactivators that increase the specificity of AP-1 transcription factors

21 January 2018

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A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors

21 January 2018

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The interferon-inducible p202 protein as a modulator of transcription: inhibition of NF-kappa B, c-Fos, and c-Jun activities

21 January 2018

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Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway

21 January 2018

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Rac is required for v-Abl tyrosine kinase to activate mitogenesis

21 January 2018

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Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins

21 January 2018

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Src homology 2 domain as a specificity determinant in the c-Abl-mediated tyrosine phosphorylation of the RNA polymerase II carboxyl-terminal repeated domain

21 January 2018

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Expression of interferon consensus sequence binding protein (ICSBP) is downregulated in Bcr-Abl-induced murine chronic myelogenous leukemia-like disease, and forced coexpression of ICSBP inhibits Bcr-Abl-induced myeloproliferative disorder

21 January 2018

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MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases

21 January 2018

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Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain

21 January 2018

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A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

21 January 2018

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Cloning and characterization of Dlk, a novel serine/threonine kinase that is tightly associated with chromatin and phosphorylates core histones

21 January 2018

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Dynamic relocation of transcription and splicing factors dependent upon transcriptional activity

21 January 2018

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Nuclear targeting determinants of the far upstream element binding protein, a c-myc transcription factor

21 January 2018

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Identification of heterogeneous nuclear ribonucleoprotein K (hnRNP K) as a repressor of C/EBPbeta-mediated gene activation

21 January 2018

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Transcriptional induction of the alpha-1 acid glycoprotein (AGP) gene by synergistic interaction of two alternative activator forms of AGP/enhancer-binding protein (C/EBP beta) and NF-kappaB or Nopp140.

21 January 2018

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Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region

21 January 2018

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The Nck SH2/SH3 adaptor protein is present in the nucleus and associates with the nuclear protein SAM68

21 January 2018

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Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein

21 January 2018

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Activation of the Abl tyrosine kinase in vivo by Src homology 3 domains from the Src homology 2/Src homology 3 adaptor Nck.

21 January 2018

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The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M107030200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11514578%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference