Tumor acidity, ion trapping and chemotherapeutics. I. Acid pH affects the distribution of chemotherapeutic agents in vitro (Q28204576)

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Breast conservation is a safe method in patients with small cancer of the breast. Long-term results of three randomised trials on 1,973 patients.

7 January 2021

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Radiation therapy and survival in breast cancer patients with 10 or more positive axillary lymph nodes treated with mastectomy

7 January 2021

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Reanalysis and results after 12 years of follow-up in a randomized clinical trial comparing total mastectomy with lumpectomy with or without irradiation in the treatment of breast cancer

7 January 2021

1 reference

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Adjuvant chemotherapy in operable breast cancer: cyclophosphamide, methotrexate, and fluorouracil versus chlorambucil, methotrexate, and fluorouracil--11-year results of Swiss Group for Clinical Cancer Research trial SAKK 27/82

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

pH and drug resistance. II. turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

MRI of the tumor microenvironment.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

pH and drug resistance in tumors.

7 January 2021

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The relevance of tumour pH to the treatment of malignant disease

7 January 2021

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Plasmalemmal pH-gradients in drug-sensitive and drug-resistant MCF-7 human breast carcinoma xenografts measured by 31P magnetic resonance spectroscopy

7 January 2021

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Measurement of the extracellular pH of solid tumours in mice by magnetic resonance spectroscopy: a comparison of exogenous (19)F and (31)P probes

7 January 2021

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In vivo imaging of extracellular pH using1H MRSI

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Combined vascular and extracellular pH imaging of solid tumors

7 January 2021

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Studies of human tumors by MRS: a review

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Effects of agents which inhibit the regulation of intracellular pH on murine solid tumours

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Acidic environment modifies heat- or radiation-induced apoptosis in human maxillary cancer cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

A comparison of cyclophosphamide, adriamycin, and 5-fluorouracil (CAF) and cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, and prednisone (CMFVP) in patients with advanced breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Combination chemotherapy with cyclophosphamide, vincristine, adriamycin, and dexamethasone (CVAD) plus oral quinine and verapamil in patients with advanced breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Different mechanisms of decreased drug accumulation in doxorubicin and mitoxantrone resistant variants of the MCF7 human breast cancer cell line

7 January 2021

1 reference

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Adriamycin (14-hydroxydaunomycin), a novel antitumor antibiotic

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

ATP-dependent uptake of anti-neoplastic agents by acidic organelles.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

pH and drug resistance. I. functional expression of plasmalemmal V-type H+-ATPase in drug-resistant human breast carcinoma cell lines

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Reversal of doxorubicin resistance and catalytic neutralization of lysosomes by a lipophilic imidazole

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Tamoxifen inhibits acidification in cells independent of the estrogen receptor

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Selectivity of the anthracyclines for negatively charged model membranes: role of the amino group

7 January 2021

1 reference

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Binding of transferrin-iron by adriamycin at acidic pH

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Intracellular pH does not affect drug extrusion by P-glycoprotein

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Transport and binding of daunorubicin, adriamycin, and rubidazone in ehrlich ascites tumour cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Comparison of the interaction of doxorubicin, daunorubicin, idarubicin and idarubicinol with large unilamellar vesicles. Circular dichroism study

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

P-glycoprotein preferentially effluxes anthracyclines containing free basic versus charged amine

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Mitoxantrone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the chemotherapy of cancer

7 January 2021

1 reference

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Mitoxantrone: an active, new antitumor agent with an improved therapeutic index

7 January 2021

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Effects of DNA intercalating agents on topoisomerase II induced DNA strand cleavage in isolated mammalian cell nuclei

7 January 2021

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Influence of low pH on cytotoxicity of paclitaxel, mitoxantrone and topotecan

7 January 2021

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Determination of mitoxantrone in mouse whole blood and different tissues by high-performance liquid chromatography

7 January 2021

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Taxol stabilizes microtubules in mouse fibroblast cells

7 January 2021

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The taxoids: paclitaxel (Taxol) and docetaxel (Taxotere).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Chemotherapeutic action of a cyclic nitrogen mustard phosphamide ester (B 518-ASTA) in experimental tumours of the rat.

7 January 2021

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Increased drug cytotoxicity at reduced pH counteracts cyclophosphamide resistance in cultured rat mammary carcinoma cells.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Phosphorus-31 NMR investigations of phosphoramide mustard: evaluation of pH control over the rate of intramolecular cyclization to an aziridinium ion and the hydrolysis of this reactive alkylator

7 January 2021

1 reference

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The metabolism of chlorambucil

7 January 2021

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Glutathione-S-transferase P-form dependent chlorambucil resistance in Yoshida rat ascites hepatoma cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Extracellular pH, transmembrane distribution and cytotoxicity of chlorambucil.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

The effect of hypoxia and low pH on the cytotoxicity of chlorambucil

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Potentiation of anti-cancer drug activity at low intratumoral pH induced by the mitochondrial inhibitor m-iodobenzylguanidine (MIBG) and its analogue benzylguanidine (BG).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Fluorouracil: biochemistry and pharmacology

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Influence of pH on the uptake of 5-fluorouracil into isolated tumour cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Enhancement of chemotherapy by manipulation of tumour pH.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Determination of cell number in monolayer cultures

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Role of pH in tumor-trapping of the anticancer drug 5-fluorouracil

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Enhanced uptake of ifosfamide into GH3 prolactinomas with hypercapnic hyperoxic gases monitored in vivo by (31)P MRS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2

Protection of cultured malignant cells from mitoxantrone cytotoxicity by low extracellular pH: a possible mechanism for chemoresistance in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900467-2