Akt2 Negatively Regulates Assembly of the POSH-MLK-JNK Signaling Complex (Q28204417)

https://api.crossref.org/works/10.1074/JBC.M307357200

mitogen-activated protein (MAP) kinase, JNK

13 March 2024

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14504284

signal transducing adaptor protein

13 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14504284

13 March 2024

signal transduction

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14504284

13 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307357200

13 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307357200

13 March 2024

author name string

Claudia Figueroa

1

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Samantha Tarras

2

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Jennifer Taylor

3

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Anne B. Vojtek

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14504284

13 March 2024

language of work or name

English

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publication date

28 November 2003

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21 September 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14504284

full work available at URL

13 March 2024

http://www.jbc.org/content/278/48/47922.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14504284

https://api.elsevier.com/content/article/PII:S0021925820758229?httpAccept=text/xml

13 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307357200

https://api.elsevier.com/content/article/PII:S0021925820758229?httpAccept=text/plain

13 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307357200

https://syndication.highwire.org/content/doi/10.1074/jbc.M307357200

13 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307357200

Journal of Biological Chemistry

13 March 2024

published in

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volume

278

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issue

48

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page(s)

47922-7

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cites work

Cellular survival: a play in three Akts

1 reference

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PKB/AKT: functional insights from genetic models

21 January 2018

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PKB binding proteins. Getting in on the Akt.

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

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Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

1 reference

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Negative regulation of the serine/threonine kinase B-Raf by Akt

21 January 2018

1 reference

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Negative regulation of mixed lineage kinase 3 by protein kinase B/AKT leads to cell survival

21 January 2018

1 reference

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Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation

21 January 2018

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Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

21 January 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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Mixed-lineage kinase control of JNK and p38 MAPK pathways

21 January 2018

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The JNK signal transduction pathway

21 January 2018

1 reference

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Rho GTPases and their effector proteins

21 January 2018

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Akt1 regulates a JNK scaffold during excitotoxic apoptosis

21 January 2018

1 reference

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A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307357200

POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

21 January 2018

1 reference

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

1 reference

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Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate

21 January 2018

1 reference

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Role of MLK3-mediated activation of p70 S6 kinase in Rac1 transformation

21 January 2018

1 reference

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Autoinhibition of mixed lineage kinase 3 through its Src homology 3 domain

21 January 2018

1 reference

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AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation

21 January 2018

1 reference

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Structure-function analysis of SH3 domains: SH3 binding specificity altered by single amino acid substitutions

21 January 2018

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Role of the conserved acidic residue Asp21 in the structure of phosphatidylinositol 3-kinase Src homology 3 domain: circular dichroism and nuclear magnetic resonance studies

21 January 2018

1 reference

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A novel, specific interaction involving the Csk SH3 domain and its natural ligand

21 January 2018

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High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate

21 January 2018

1 reference

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JNK-interacting protein 1 promotes Akt1 activation.

21 January 2018

1 reference

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Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation

21 January 2018

1 reference

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The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M307357200

13 March 2024

Identifiers

0 references