Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5 (Q28203836)

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7 January 2021

Structure and dynamics of molecular motors

1 reference

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7 January 2021

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900212-0

7 January 2021

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900212-0

7 January 2021

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900212-0

7 January 2021

Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle

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7 January 2021

1 reference

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7 January 2021

Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryos

1 reference

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7 January 2021

Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker

1 reference

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7 January 2021

Decoupling of nucleotide- and microtubule-binding sites in a kinesin mutant

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900212-0

7 January 2021

A kinesin mutation that uncouples motor domains and desensitizes the gamma-phosphate sensor

1 reference

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7 January 2021

Influence of the kinesin neck domain on dimerization and ATPase kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900212-0

7 January 2021

Kinesin has three nucleotide-dependent conformations. Implications for strain-dependent release

1 reference

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7 January 2021

Microtubule interaction site of the kinesin motor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900212-0

7 January 2021

Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue.

1 reference

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7 January 2021

Allele-specific activators and inhibitors for kinesin

1 reference

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7 January 2021

100 years of the biginelli dihydropyrimidine synthesis

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7 January 2021

How to measure and predict the molar absorption coefficient of a protein

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900212-0

7 January 2021

New ribose-modified fluorescent analogs of adenine and guanine nucleotides available as subtrates for various enzymes

1 reference

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7 January 2021

Actin-dependent motile forces and cell motility

1 reference

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7 January 2021

A hot spot of binding energy in a hormone-receptor interface

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900212-0

7 January 2021

Protein kinases--the major drug targets of the twenty-first century?

1 reference

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7 January 2021

Structure-based design of cyclin-dependent kinase inhibitors

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7 January 2021

Allosteric drugs: thinking outside the active-site box.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900212-0

7 January 2021

Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900212-0

7 January 2021

The novel and specific Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine as a probing molecule for Rho-kinase-involved pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900212-0

7 January 2021