Alpha4 integrins and the immune response (Q28202046)

25 May 2017

author name string

David M Rose

1

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Jaewon Han

2

1 reference

25 May 2017

Mark H Ginsberg

3

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David M. Rose

1

1 reference

25 May 2017

Mark H. Ginsberg

3

1 reference

25 May 2017

language of work or name

English

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publication date

August 2002

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25 May 2017

published in

Immunological Reviews

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25 May 2017

volume

186

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25 May 2017

page(s)

118-24

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118-124

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25 May 2017

issue

1

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

25 May 2017

1 reference

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

Very late antigen 4 (VLA4) antagonists as anti-inflammatory agents

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

Selective, tight-binding inhibitors of integrin alpha4beta1 that inhibit allergic airway responses

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

Intact LIM 3 and LIM 4 domains of paxillin are required for the association to a novel polyproline region (Pro 2) of protein-tyrosine phosphatase-PEST

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

Direct association of protein-tyrosine phosphatase PTP-PEST with paxillin

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

Integrins take partners: cross-talk between integrins and other membrane receptors

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

Phosphorylation of the integrin alpha 4 cytoplasmic domain regulates paxillin binding

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

A truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylation

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

Lymphocyte trafficking and regional immunity.

28 May 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Differential requirements for alpha4 integrins during fetal and adult hematopoiesis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

In vivo roles of integrins during leukocyte development and traffic: insights from the analysis of mice chimeric for alpha 5, alpha v, and alpha 4 integrins

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Rheumatoid arthritis synovial stromal cells inhibit apoptosis and up-regulate Bcl-xL expression by B cells in a CD49/CD29-CD106-dependent mechanism

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Cell adhesion and migration are regulated at distinct stages of thymic T cell development: the roles of fibronectin, VLA4, and VLA5.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Alpha4 integrins regulate the proliferation/differentiation balance of multilineage hematopoietic progenitors in vivo

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

VLA-4-mediated interactions between normal human hematopoietic progenitors and stromal cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Molecular pathways in bone marrow homing: dominant role of alpha(4)beta(1) over beta(2)-integrins and selectins

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Synergistic mobilization of hemopoietic progenitor cells using concurrent beta1 and beta2 integrin blockade or beta2-deficient mice.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Critical role for β7 integrins in formation of the gut-associated lymphoid tissue

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Beta1 integrin is not essential for hematopoiesis but is necessary for the T cell-dependent IgM antibody response

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Distinct cell surface ligands mediate T lymphocyte attachment and rolling on P and E selectin under physiological flow.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

The affinity of integrin alpha(4)beta(1) governs lymphocyte migration

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Subsecond induction of alpha4 integrin clustering by immobilized chemokines stimulates leukocyte tethering and rolling on endothelial vascular cell adhesion molecule 1 under flow conditions

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Chemokines trigger immediate beta2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Alpha 4 beta 1 integrin/VCAM-1 interaction activates alpha L beta 2 integrin-mediated adhesion to ICAM-1 in human T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Alpha 4-integrins mediate antigen-induced late bronchial responses and prolonged airway hyperresponsiveness in sheep

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

The pathophysiologic role of alpha 4 integrins in vivo

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Monoclonal antibodies to the integrin alpha-4 subunit inhibit the murine contact hypersensitivity response.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

The use of lymphocyte function-associated antigen (LFA)-1-deficient mice to determine the role of LFA-1, Mac-1, and alpha4 integrin in the inflammatory response of neutrophils.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Functional alpha4-integrin: a newly identified pathway of neutrophil recruitment in critically ill septic patients

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

The alpha4-integrin: an alternative pathway for neutrophil recruitment?

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

The effect of anti-alpha4 integrin antibody on brain lesion activity in MS. The UK Antegren Study Group.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Therapeutic intervention with inhibitors of co-stimulatory pathways in autoimmune disease

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Blockade of late-phase airway responses and airway hyperresponsiveness in allergic sheep with a small-molecule peptide inhibitor of VLA-4

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Survival signals within the tumour microenvironment suppress drug-induced apoptosis: lessons learned from B lymphomas

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Distinct cellular functions mediated by different VLA integrin alpha subunit cytoplasmic domains

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Specialized functional properties of the integrin alpha 4 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Signal transduction by cell adhesion receptors and the cytoskeleton: functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Paxillin binding to a conserved sequence motif in the alpha 4 integrin cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

1 reference

7 January 2021

SH3 domains direct cellular localization of signaling molecules

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Integrin cross talk: activation of lymphocyte function-associated antigen-1 on human T cells alters alpha4beta1- and alpha5beta1-mediated function.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Cross-talk between phorbol ester-mediated signaling and tyrosine kinase proto-oncogenes. I. Activation of protein kinase C stimulates tyrosine phosphorylation and activation of ErbB2 and ErbB3.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Cholecystokinin-stimulated tyrosine phosphorylation of p125FAK and paxillin is mediated by phospholipase C-dependent and -independent mechanisms and requires the integrity of the actin cytoskeleton and participation of p21rho

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Requirement for diacylglycerol and protein kinase C in HeLa cell-substratum adhesion and their feedback amplification of arachidonic acid production for optimum cell spreading

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Dissection of Pathways Implicated in Integrin-mediated Actin Cytoskeleton Assembly

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Csk suppression of Src involves movement of Csk to sites of Src activity

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Regulation of cytoskeleton organization and paxillin dephosphorylation by cAMP. Studies on murine Y1 adrenal cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Hepatocyte growth factor induces ERK-dependent paxillin phosphorylation and regulates paxillin-focal adhesion kinase association

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021

Serine/threonine protein phosphatases

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18611.X

7 January 2021