The SLC22 drug transporter family (Q28190073)

https://scigraph.springernature.com/pub.10.1007/s00424-003-1089-9

Europe PubMed Central

title

The SLC22 drug transporter family (English)

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author name string

Hermann Koepsell

series ordinal

1

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Hitoshi Endou

series ordinal

2

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language of work or name

English

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publication date

February 2004

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published in

Pfluegers Archiv

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volume

447

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page(s)

666-76

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issue

5

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exact match

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cites work

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A novel putative transporter maps to the osteosclerosis (oc) mutation and is not expressed in the oc mutant mouse.

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Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine

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Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels

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Cloning and characterization of two human polyspecific organic cation transporters

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Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters

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Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2

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Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function

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Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient

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Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta

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Mechanism of electrogenic cation transport by the cloned organic cation transporter 2 from rat.

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Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney

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Role of human organic anion transporter 4 in the transport of ochratoxin A.

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Cloning of a human renal p-aminohippurate transporter, hROAT1

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Expression cloning and characterization of ROAT1. The basolateral organic anion transporter in rat kidney

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Organic cation transporters in intestine, kidney, liver, and brain

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Cationic amino acids involved in dicarboxylate binding of the flounder renal organic anion transporter

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Localization of organic cation transporters OCT1 and OCT2 in rat kidney

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Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1

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The multispecific organic anion transporter (OAT) family.

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Expression cloning and characterization of a renal organic anion transporter from winter flounder

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Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate

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Regulation of human organic cation transporter hOCT2 by PKA, PI3K, and calmodulin-dependent kinases

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Molecular cloning and characterization of high-affinity carnitine transporter from rat intestine

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Organic cation transporters

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Molecular and functional characterization of organic cation/carnitine transporter family in mice

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Molecular identification of a renal urate anion exchanger that regulates blood urate levels

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The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP.

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Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

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Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition

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Functional and pharmacological characterization of human Na(+)-carnitine cotransporter hOCTN2.

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Organic cation transporter mRNA and function in the rat superior cervical ganglion.

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Expression cloning and characterization of a novel multispecific organic anion transporter

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Identification of multispecific organic anion transporter 2 expressed predominantly in the liver

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Molecular cloning and characterization of a novel liver-specific transport protein

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Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene

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cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2.

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Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

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Organic cation transporter capable of transporting serotonin is up-regulated in serotonin transporter-deficient mice.

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Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain

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Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2.

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Immunolocalization of multispecific organic anion transporters, OAT1, OAT2, and OAT3, in rat kidney

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Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance

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Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors.

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Na(+)-coupled transport of L-carnitine via high-affinity carnitine transporter OCTN2 and its subcellular localization in kidney

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Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter

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Mutations in novel organic cation transporter (OCTN2), an organic cation/carnitine transporter, with differential effects on the organic cation transport function and the carnitine transport function

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Release of non-neuronal acetylcholine from the isolated human placenta is mediated by organic cation transporters

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Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta

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Drug excretion mediated by a new prototype of polyspecific transporter

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Isolation of a family of organic anion transporters from human liver and kidney

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Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta

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Transport of organic anions across the basolateral membrane of proximal tubule cells

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cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family

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Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations

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Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences

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Studies on functional sites of organic cation/carnitine transporter OCTN2 (SLC22A5) using a Ser467Cys mutant protein

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Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney

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Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain

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The affinity of the organic cation transporter rOCT1 is increased by protein kinase C-dependent phosphorylation

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Cloning and functional expression of a human liver organic cation transporter

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Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins.

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Identification of OCT6 as a novel organic cation transporter preferentially expressed in hematopoietic cells and leukemias

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Organic anion and cation transporters occur in pairs of similar and similarly expressed genes

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12 December 2020

Impaired activity of the extraneuronal monoamine transporter system known as uptake-2 in Orct3/Slc22a3-deficient mice

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12 December 2020