Mitochondrial uncoupling protein 2 in the central nervous system: neuromodulator and neuroprotector (Q28176789)

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4 November 2019

review article

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title

Mitochondrial uncoupling protein 2 in the central nervous system: neuromodulator and neuroprotector (English)

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4 November 2019

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3

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4 November 2019

author name string

Tamas L Horvath

series ordinal

1

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4 November 2019

Sabrina Diano

series ordinal

2

1 reference

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4 November 2019

language of work or name

English

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publication date

1 June 2003

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4 November 2019

published in

Biochemical Pharmacology

1 reference

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4 November 2019

volume

65

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4 November 2019

issue

12

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4 November 2019

page(s)

1917-1921

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Molecular approach to thermogenesis in brown adipose tissue: cDNA cloning of the mitochondrial uncoupling protein

4 November 2019

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Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

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Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression

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UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue

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UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells

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BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast

7 January 2021

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A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation

7 January 2021

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Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

7 January 2021

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Thermogenic mechanisms in brown fat

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Towards a molecular understanding of adaptive thermogenesis

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Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts

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Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

7 January 2021

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Brain uncoupling protein 2: uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers.

7 January 2021

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Mitochondrial uncoupling protein 2 (UCP2) in the nonhuman primate brain and pituitary

7 January 2021

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Mitochondrial proton leak and the uncoupling proteins

7 January 2021

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Overexpression of UCP3 in cultured human muscle lowers mitochondrial membrane potential, raises ATP/ADP ratio, and favors fatty acid vs. glucose oxidation.

7 January 2021

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Expression of the uncoupling protein 1 from the aP2 gene promoter stimulates mitochondrial biogenesis in unilocular adipocytes in vivo

7 January 2021

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

7 January 2021

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Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells.

7 January 2021

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Oxidative stress, mitochondrial function, and acute glutamate excitotoxicity in cultured cerebellar granule cells.

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Uncoupling protein 2, in vivo distribution, induction upon oxidative stress, and evidence for translational regulation

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Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants

7 January 2021

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Superoxide activates mitochondrial uncoupling proteins

7 January 2021

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Brain mitochondrial uncoupling protein 2 (UCP2): a protective stress signal in neuronal injury.

7 January 2021

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Uncoupling protein 2 in primary pain and temperature afferents of the spinal cord.

7 January 2021

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Uncoupling protein 2 (UCP2) lowers alcohol sensitivity and pain threshold

7 January 2021

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Coenzyme Q is an obligatory cofactor for uncoupling protein function

7 January 2021

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Uncoupling proteins 2 and 3 are highly active H(+) transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)

7 January 2021

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Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin

7 January 2021

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Uncoupling protein-3: a muscle-specific gene upregulated by leptin in ob/ob mice

7 January 2021

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Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation

7 January 2021

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Enhanced expression of uncoupling protein 2 gene in rat white adipose tissue and skeletal muscle following chronic treatment with thyroid hormone

7 January 2021

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A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans

7 January 2021

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9-cis Retinoic acid induces the expression of the uncoupling protein-2 gene in brown adipocytes

7 January 2021

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Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2.

7 January 2021

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Bacterial lipopolysaccharide induces uncoupling protein-2 expression in hepatocytes by a tumor necrosis factor-alpha-dependent mechanism

7 January 2021

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10.1016/S0006-2952(03)00143-6

7 January 2021

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12787871%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017