Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1 (Q28138472)

1

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Z Wu

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G Adelmant

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P Puigserver

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M Fan

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B M Spiegelman

Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells.

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language of work or name

English

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publication date

August 2000

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published in

Molecular Cell

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volume

6

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page(s)

307-16

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issue

2

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cites work

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7 January 2021

The intracisternal A-particle proximal enhancer-binding protein activates transcription and is identical to the RNA- and DNA-binding protein p54nrb/NonO.

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Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains

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Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity

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mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain

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Allosteric interactions between capping enzyme subunits and the RNA polymerase II carboxy-terminal domain

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A CTD function linking transcription to splicing

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Functional association between promoter structure and transcript alternative splicing.

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Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer

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7 January 2021

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes

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7 January 2021

Did nucleotides or amino acids drive evolutionary conservation of the WT1 +/-KTS alternative splice?

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A specific isoform of hnRNP D interacts with DNA in the LR1 heterodimer: canonical RNA binding motifs in a sequence-specific duplex DNA binding protein

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7 January 2021

HRS/SRp40-mediated inclusion of the fibronectin EIIIB exon, a possible cause of increased EIIIB expression in proliferating liver

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7 January 2021

Differential effects of heterogeneous nuclear ribonucleoprotein K on Sp1- and Sp3-mediated transcriptional activation of a neuronal nicotinic acetylcholine receptor promoter

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7 January 2021

The glucocorticoid receptor is associated with the RNA-binding nuclear matrix protein hnRNP U

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7 January 2021

WT1--more than a transcription factor?

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7 January 2021

Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

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7 January 2021

A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2

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7 January 2021

A serine kinase regulates intracellular localization of splicing factors in the cell cycle

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7 January 2021

Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors

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7 January 2021

The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA-binding protein p54nrb

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7 January 2021

The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS

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Nucleolin is one component of the B cell-specific transcription factor and switch region binding protein, LR1.

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7 January 2021

RNA polymerase II is an essential mRNA polyadenylation factor

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7 January 2021

Phosphorylated RNA polymerase II stimulates pre-mRNA splicing

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7 January 2021

Elements regulating an alternatively spliced exon of the rat fibronectin gene

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7 January 2021

Peroxisome proliferator-activated receptors gamma and alpha mediate in vivo regulation of uncoupling protein (UCP-1, UCP-2, UCP-3) gene expression.

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7 January 2021

Splicing factors associate with hyperphosphorylated RNA polymerase II in the absence of pre-mRNA

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7 January 2021

The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs)

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7 January 2021

hnRNP complexes: composition, structure, and function

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7 January 2021

Presence of WT1, the Wilm's tumor suppressor gene product, in nuclear poly(A)(+) ribonucleoprotein

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7 January 2021

A human papillomavirus E2 transcriptional activator. The interactions with cellular splicing factors and potential function in pre-mRNA processing

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7 January 2021

The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin

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7 January 2021

The Wilms' tumor suppressor gene (wt1) product represses different functional classes of transcriptional activation domains

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7 January 2021

Nuclear receptor that identifies a novel retinoic acid response pathway

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7 January 2021

Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase

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7 January 2021

Substrate specificities of SR proteins in constitutive splicing are determined by their RNA recognition motifs and composite pre-mRNA exonic elements

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7 January 2021

5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II

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7 January 2021

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

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7 January 2021

Heterogeneous nuclear ribonucleoprotein K is a transcription factor

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7 January 2021

Serine/threonine phosphatase 1 modulates the subnuclear distribution of pre-mRNA splicing factors

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7 January 2021

RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo

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7 January 2021

The dynamics of a pre-mRNA splicing factor in living cells

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7 January 2021

Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo

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7 January 2021

The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation

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7 January 2021

The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins

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7 January 2021

A novel RNA polymerase II-containing complex potentiates Tat-enhanced HIV-1 transcription

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7 January 2021

Identification of a cyclin subunit required for the function of Drosophila P-TEFb

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7 January 2021

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

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7 January 2021

Activation of PPARgamma coactivator-1 through transcription factor docking

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7 January 2021

Multiple RNA binding domains (RBDs) just don't add up

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7 January 2021

Determinants of SR protein specificity.

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7 January 2021

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer

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7 January 2021

The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes

1 reference

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7 January 2021

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

1 reference

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7 January 2021

Transcription elongation factor hSPT5 stimulates mRNA capping

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7 January 2021

A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme

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7 January 2021

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

1 reference

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7 January 2021

NonO enhances the association of many DNA-binding proteins to their targets

1 reference

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7 January 2021

Nucleolin, a novel partner for the Myb transcription factor family that regulates their activity

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7 January 2021

10.1016/S1097-2765(00)00031-9

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

2136735

2136735

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference