LC/MS applications in drug development (Q28138241)

Europe PubMed Central

title

LC/MS applications in drug development (English)

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author name string

M S Lee

series ordinal

1

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E H Kerns

series ordinal

2

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language of work or name

English

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publication date

1999

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Mass Spectrometry Reviews

PubMed

published in

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volume

18

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issue

3-4

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page(s)

187-279

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cites work

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Structural characterization of protein tryptic peptides via liquid chromatography/mass spectrometry and collision-induced dissociation of their doubly charged molecular ions

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Reversed-phase peptide mapping of glycoproteins using liquid chromatography/electrospray ionization-mass spectrometry

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21 January 2018

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Structural elucidation of drug metabolites by triple-quadrupole mass spectrometry

21 January 2018

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Carbohydrate molecular weight profiling, sequence, linkage, and branching data: ES-MS and CID.

21 January 2018

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Proposal for a common nomenclature for sequence ions in mass spectra of peptides

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Predictive strategy for the rapid structure elucidation of drug degradants

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Investigation of the CNS penetration of a potent 5-HT2a receptor antagonist (MDL 100,907) and an active metabolite (MDL 105,725) using in vivo microdialysis sampling in the rat.

21 January 2018

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21 January 2018

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Rapid 'de novo' peptide sequencing by a combination of nanoelectrospray, isotopic labeling and a quadrupole/time-of-flight mass spectrometer.

21 January 2018

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Coupling capillary high-performance liquid chromatography to matrix-assisted laser desorption/ionization mass spectrometry and N-terminal sequencing of peptides via automated microblotting onto membrane substrates.

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'Metabolic mapping' of drugs: rapid screening techniques for xenobiotic metabolites with m.s./m.s. techniques

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The identification of peptide modifications derived from gel-separated proteins using electrospray triple quadrupole and ion trap analyses

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A liquid chromatography/electrospray mass spectrometric study on the post-transcriptional modification of tRNA.

21 January 2018

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Open access atmospheric pressure chemical ionization Mass spectrometry for routine sample analysis

21 January 2018

1 reference

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Sildenafil (VIAGRATM), a potent and selective inhibitor of type 5 cGMP phosphodiesterase with utility for the treatment of male erectile dysfunction

21 January 2018

1 reference

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Application of liquid chromatography-mass spectrometry(n) analyses to the characterization of novel glyburide metabolites formed in vitro

21 January 2018

1 reference

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Pulsed ultrafiltration mass spectrometry: a new method for screening combinatorial libraries.

21 January 2018

1 reference

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Profiling impurities and degradants of butorphanol tartrate using liquid chromatography/mass spectrometry and liquid chromatography/tandem mass spectrometry substructural techniques

21 January 2018

1 reference

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Studies on the metabolism of omeprazole in the rat using liquid chromatography/ionspray mass spectrometry and the isotope cluster technique with [34S]omeprazole

21 January 2018

1 reference

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Electrospray-ionization mass spectrometry of intact intrinsic membrane proteins

21 January 2018

1 reference

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Analytical properties of the nanoelectrospray ion source

21 January 2018

1 reference

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Deconvolution of combinatorial libraries for drug discovery: experimental comparison of pooling strategies

21 January 2018

1 reference

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Peptide mass maps: a highly informative approach to protein identification

21 January 2018

1 reference

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Mass spectrometry and the age of the proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291098-2787%281999%2918%3A3%2F4%3C187%3A%3AAID-MAS2%3E3.0.CO%3B2-K

Method to compare collision-induced dissociation spectra of peptides: potential for library searching and subtractive analysis

21 January 2018

1 reference

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Database searching using mass spectrometry data

21 January 2018

1 reference

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Tandem mass spectrometry: quadrupole and hybrid instruments

21 January 2018

1 reference

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Identification of in vitro metabolites of Indinavir by "intelligent automated LC-MS/MS" (INTAMS) utilizing triple quadrupole tandem mass spectrometry.

21 January 2018

1 reference

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A double-blind comparison of oral butorphanol and codeine

21 January 2018

1 reference

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The observation of non-covalent interactions in solution by electrospray ionization mass spectrometry: Promise, pitfalls and prognosis

21 January 2018

1 reference

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21 January 2018

Perfusion chromatography

1 reference

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