The parkin-like human homolog of Drosophila ariadne-1 (HHARI) can induce aggresome formation in mammalian cells and is immunologically detectable in Lewy bodies (Q28117293)

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English	The parkin-like human homolog of Drosophila ariadne-1 (HHARI) can induce aggresome formation in mammalian cells and is immunologically detectable in Lewy bodies	scientific journal article

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scholarly article

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4 January 2017

The parkin-like human homolog of Drosophila ariadne-1 (HHARI) can induce aggresome formation in mammalian cells and is immunologically detectable in Lewy bodies (English)

1 reference

4 January 2017

Ariadne RBR E3 ubiquitin protein ligase 1

1 reference

GOA release 2020-03-11

author name string

Sangram S. Parelkar

1

1 reference

4 January 2017

Juan G. Cadena

2

1 reference

4 January 2017

Chul Kim

3

1 reference

4 January 2017

Zhaohui Wang

4

1 reference

4 January 2017

Rachel Sugal

5

1 reference

4 January 2017

Brooke Bentley

6

1 reference

4 January 2017

Luis Moral

7

1 reference

4 January 2017

Helen C. Ardley

8

1 reference

4 January 2017

Lawrence M. Schwartz

9

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4 January 2017

publication date

1 January 2012

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4 January 2017

Journal of Molecular Neuroscience

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4 January 2017

46

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4 January 2017

1

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4 January 2017

109–121

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4 January 2017

https://scigraph.springernature.com/pub.10.1007/s12031-011-9535-1

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Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Structure of the C-terminal RING finger from a RING-IBR-RING/TRIAD motif reveals a novel zinc-binding domain distinct from a RING

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Co-association of parkin and alpha-synuclein

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkinson's disease: insights from pathways

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

The role of parkin in familial and sporadic Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkin-mediated ubiquitination regulates phospholipase C-gamma1.

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Programmed cell death-2 isoform1 is ubiquitinated by parkin and increased in the substantia nigra of patients with autosomal recessive Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Aggresomes: a cellular response to misfolded proteins

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkin accumulation in aggresomes due to proteasome impairment

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkin cleaves intracellular alpha-synuclein inclusions via the activation of calpain

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Brain stem pathology in Parkinson's disease: an evaluation of the Braak staging model

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Aggresomes, inclusion bodies and protein aggregation

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

The effects of oxidative stress on parkin and other E3 ligases

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkinson's disease: from monogenic forms to genetic susceptibility factors

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Comparative genomics of the RBR family, including the Parkinson's disease-related gene parkin and the genes of the ariadne subfamily

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Aggresome-related biogenesis of Lewy bodies

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Transcription factor single-minded 2 (SIM2) is ubiquitinated by the RING-IBR-RING-type E3 ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Lewy-body formation is an aggresome-related process: a hypothesis

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkin-mediated K63-linked polyubiquitination: a signal for targeting misfolded proteins to the aggresome-autophagy pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Differential interaction of the E3 ligase parkin with the proteasomal subunit S5a and the endocytic protein Eps15.

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Diagnosis and treatment of Parkinson disease: molecules to medicine

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkinsonism proteolysis and proteasomes

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Familial juvenile parkinsonism: clinical and pathologic study in a family.

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Mechanisms of neuronal death in synucleinopathy

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Functional modulation of parkin through physical interaction with SUMO-1.

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Pael-R transgenic mice crossed with parkin deficient mice displayed progressive and selective catecholaminergic neuronal loss

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Dynamic association of proteasomal machinery with the centrosome

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

DNA internalized via caveolae requires microtubule-dependent, Rab7-independent transport to the late endocytic pathway for delivery to the nucleus

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Relative sensitivity of parkin and other cysteine-containing enzymes to stress-induced solubility alterations

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Familial juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

1 reference

https://api.crossref.org/works/10.1007%2FS12031-011-9535-1

21 January 2018

Ariadne-1: a vital Drosophila gene is required in development and defines a new conserved family of ring-finger proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21590270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synphilin-1 is present in Lewy bodies in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21590270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant Folding of Pathogenic Parkin Mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/21590270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Update in the epidemiology of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21590270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteinaceous intracellular inclusions in neurodegenerative disorders.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21590270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of proteasome inhibition by MG-132 on HSP27 oligomerization, phosphorylation, and aggresome formation in the OLN-93 oligodendroglia cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/21590270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Etiology of Parkinson's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21590270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assembly of lysine 63-linked ubiquitin conjugates by phosphorylated alpha-synuclein implies Lewy body biogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21590270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggresome formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21590270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathology of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21590270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21590270

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12031-011-9535-1

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1 reference

4 January 2017

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