Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes (Q28115888)

Multiple EGF-like-domains 10

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Tal Iram

1

1 reference

4 January 2017

Zaida Ramirez-Ortiz

2

1 reference

4 January 2017

Michael H. Byrne

3

1 reference

4 January 2017

Uwanda A. Coleman

4

1 reference

4 January 2017

Nathan D. Kingery

5

1 reference

4 January 2017

Terry K. Means

6

1 reference

4 January 2017

Dan Frenkel

7

1 reference

4 January 2017

Joseph El Khoury

Mutations in MEGF10, a regulator of satellite cell myogenesis, cause early onset myopathy, areflexia, respiratory distress and dysphagia (EMARDD)

8

1 reference

4 January 2017

language of work or name

English

0 references

publication date

11 May 2016

1 reference

4 January 2017

Journal of Neuroscience

1 reference

4 January 2017

36

1 reference

4 January 2017

19

1 reference

4 January 2017

5185–5192

1 reference

4 January 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Cysteine mutations cause defective tyrosine phosphorylation in MEGF10 myopathy

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

The classical complement cascade mediates CNS synapse elimination

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Reactive astrocytes protect tissue and preserve function after spinal cord injury

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Megf10 regulates the progression of the satellite cell myogenic program

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Standardizing scavenger receptor nomenclature

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Astrocytes engage unique molecular programs to engulf pruned neuronal debris from distinct subsets of neurons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

The microglial sensome revealed by direct RNA sequencing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Scara1 deficiency impairs clearance of soluble amyloid-β by mononuclear phagocytes and accelerates Alzheimer's-like disease progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Jedi-1 and MEGF10 signal engulfment of apoptotic neurons through the tyrosine kinase Syk.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Mutations in the satellite cell gene MEGF10 cause a recessive congenital myopathy with minicores

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Neuronal apoptosis in the developing cerebellum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Journey to the grave: signaling events regulating removal of apoptotic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Unwrapping glial biology: Gcm target genes regulating glial development, diversification, and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated by serum deprivation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

YOPRO-1 permits cytofluorometric analysis of programmed cell death (apoptosis) without interfering with cell viability.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

Adult mouse astrocytes degrade amyloid-beta in vitro and in situ

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863057

10.1523/JNEUROSCI.3850-15.2016

27 November 2018

Identifiers

DOI

1 reference

4 January 2017

release_e6jbtcqxzvfsrpnhtuw4qxci2q

1 reference

Fatcat

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