Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin (Q28114773)

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English	Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin	scientific journal article

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scholarly article

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3 January 2017

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11 March 2020

Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin (English)

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3 January 2017

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11 March 2020

FMRP translational regulator 1

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GOA release 2020-03-11

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11 March 2020

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11 March 2020

Lech-Gustav Milroy

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Lech G Milroy

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11 March 2020

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Christian Herrmann

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11 March 2020

Mohamed S Taha

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11 March 2020

Jens M Moll

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11 March 2020

Roland P Piekorz

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11 March 2020

Mohammad R Ahmadian

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21 March 2014

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11 March 2020

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11 March 2020

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11 March 2020

e91465

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11 March 2020

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11 March 2020

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Creative Commons Attribution 4.0 International

21 March 2014

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0 references

The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins

1 reference

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20 March 2017

A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P

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20 March 2017

The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction

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Characterization of Staufen 1 ribonucleoprotein complexes

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20 March 2017

82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization

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The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP

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NUFIP1 (nuclear FMRP interacting protein 1) is a nucleocytoplasmic shuttling protein associated with active synaptoneurosomes

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EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

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The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs

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Oligomerization properties of fragile-X mental-retardation protein (FMRP) and the fragile-X-related proteins FXR1P and FXR2P

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Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex

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20 March 2017

The 'invisible hand': regulation of RHO GTPases by RHOGDIs

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20 March 2017

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function

1 reference

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20 March 2017

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism

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20 March 2017

Fragile x syndrome

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20 March 2017

Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2

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Nuclear Fragile X Mental Retardation Protein is localized to Cajal bodies

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FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association

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Fragile X mental retardation protein FMRP binds mRNAs in the nucleus

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Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations

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RNA-binding protein nucleolin in disease

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Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes

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Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

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FMR1 transcript isoforms: association with polyribosomes; regional and developmental expression in mouse brain

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Identification of mouse YB1/p50 as a component of the FMRP-associated mRNP particle

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The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains

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The translation of translational control by FMRP: therapeutic targets for FXS.

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Fragile X mental retardation protein and synaptic plasticity

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A novel role for the RNA-binding protein FXR1P in myoblasts cell-cycle progression by modulating p21/Cdkn1a/Cip1/Waf1 mRNA stability

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Nuclear Na+/K+-ATPase plays an active role in nucleoplasmic Ca2+ homeostasis

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Early mitochondrial abnormalities in hippocampal neurons cultured from Fmr1 pre-mutation mouse model

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Fragile X mental retardation protein interacts with the RNA-binding protein Caprin1 in neuronal RiboNucleoProtein complexes [corrected].

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Fragile X mental retardation protein: past, present and future

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New perspectives on the biology of fragile X syndrome

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Toward fulfilling the promise of molecular medicine in fragile X syndrome

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Arginines of the RGG box regulate FMRP association with polyribosomes and mRNA.

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A role for a novel protein, nucleolin, in Parkinson's disease

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S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascade

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Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

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29 September 2017

CYFIP2, a direct p53 target, is leptomycin-B sensitive

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29 September 2017

The fragile X syndrome: exploring its molecular basis and seeking a treatment.

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29 September 2017

Glyceraldehyde-3-phosphate dehydrogenase interacts with Rab2 and plays an essential role in endoplasmic reticulum to Golgi transport exclusive of its glycolytic activity

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29 September 2017

Identification of nucleolin and nucleophosmin as genotoxic stress-responsive RNA-binding proteins

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The Fragile X mental retardation protein

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29 September 2017

Alternative splicing of exon 14 determines nuclear or cytoplasmic localisation of fmr1 protein isoforms

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29 September 2017

Association of FMRP with ribosomal precursor particles in the nucleolus

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29 September 2017

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2 June 2018

The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes

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21 January 2018

The N-terminus of the fragile X mental retardation protein contains a novel domain involved in dimerization and RNA binding.

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21 January 2018

CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

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21 January 2018

The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1.

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21 January 2018

Phosphorylation influences the translation state of FMRP-associated polyribosomes

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21 January 2018

Methylation regulates the intracellular protein-protein and protein-RNA interactions of FMRP.

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21 January 2018

Drosophila FMRP regulates microtubule network formation and axonal transport of mitochondria.

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21 January 2018

Identification of novel FMR1 variants by massively parallel sequencing in developmentally delayed males.

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21 January 2018

Protein localization to the nucleolus: a search for targeting domains in nucleolin

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Solid-Phase Synthesis of Asymmetrically Branched Sequence-Defined Poly/Oligo(amidoamines)

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12 December 2020

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10.1371/JOURNAL.PONE.0091465

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11 March 2020

2014PLoSO...991465T

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11 March 2020

2 references

3 January 2017

Europe PubMed Central

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